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BP Lipid 145
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| Category | SM-102 & Analogs |
| Catalog NO. | BPG-3743 |
| Product Name | BP Lipid 145 |
| Molecular Formula | C44H87NO5 |
| Molecular Weight | 710.2 |
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| Description | BP Lipid 145 is an amino ionizable lipid with ester bonds located at C7 and C6 poisiton relative to nitrogen. The propanolamine head can effectively improve mRNA encapsulation while introduction of ester bonds improve tissue clearance. The primary ester contains a long 11 carbons tail. The ionizable lipid can be used for mRNA delivery due to its excellent physiochemical properties. |
| Synonyms | BP Lipid 145; Undecyl 7-((6-(heptadecan-9-yloxy)-6-oxohexyl)(3-hydroxypropyl)amino)heptanoate; BP-26402; CS-0435715 |
| IUPAC Name | undecyl 7-[(6-heptadecan-9-yloxy-6-oxohexyl)-(3-hydroxypropyl)amino]heptanoate |
| Canonical SMILES | CCCCCCCCCCCOC(=O)CCCCCCN(CCCCCC(=O)OC(CCCCCCCC)CCCCCCCC)CCCO |
| InChI | InChI=1S/C44H87NO5/c1-4-7-10-13-16-17-18-23-31-41-49-43(47)35-27-21-22-29-37-45(39-32-40-46)38-30-24-28-36-44(48)50-42(33-25-19-14-11-8-5-2)34-26-20-15-12-9-6-3/h42,46H,4-41H2,1-3H3 |
| InChIKey | QQBHNNIKPAXOPH-UHFFFAOYSA-N |
| Storage | -20°C |
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Industry News
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- Cholesterol: Definition, Structure, Synthesis, Types and Functions
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- PEG in Pharmaceutical Preparations (I): Solvents, Lubricants, Adhesives and More
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- PEG Linkers in Antibody Drug Conjugates and PROTACs
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- PEGylated Drugs: Definition, Structure, Classification and Benefits
- PEGylated RGD Peptides: A Promising Tool for Targeted Drug Delivery
- Pharmacokinetics and Bioanalysis of PEGylated Drugs
- Polyethylene Glycol (PEG) Modified Targeting Nanomaterials
- Preparation Method of PEG Hydrogel
- The PROTAC Technology in Drug Development
- Vaccines: Definition, History, Ingredients, Types and Mechanism of Action
- What are Lipid Excipients and Their Applications?
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