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BP Lipid 143

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Category	SM-102 & Analogs
Catalog NO.	BPG-3741
Product Name	BP Lipid 143
Molecular Formula	C40H79NO5
Molecular Weight	654.1

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Description	BP Lipid 143 is an ionizable amino lipid with propanolamine head which can efficiently encapsulate mRNA. Ester linkages are incorporated, at C7 adn C6 position relative to amine, in the structure to increase tissue clearance of the lipid in the liver. The primary ester has a 7-carbons lipid tail. The lipid can be used for mRNA-based therapies which depends on the availability of a safe and efficient delivery vehicle.
Synonyms	Heptyl 7-((6-(heptadecan-9-yloxy)-6-oxohexyl)(3-hydroxypropyl)amino)heptanoate; BP Lipid 143; BP Lipid 143?; BP-26400; CS-0435708; 2244715-87-3
IUPAC Name	heptyl 7-[(6-heptadecan-9-yloxy-6-oxohexyl)-(3-hydroxypropyl)amino]heptanoate
Canonical SMILES	CCCCCCCCC(CCCCCCCC)OC(=O)CCCCCN(CCCCCCC(=O)OCCCCCCC)CCCO
InChI	InChI=1S/C40H79NO5/c1-4-7-10-13-15-21-29-38(30-22-16-14-11-8-5-2)46-40(44)32-24-20-26-34-41(35-28-36-42)33-25-18-17-23-31-39(43)45-37-27-19-12-9-6-3/h38,42H,4-37H2,1-3H3
InChIKey	LPTJFFFRDQIERN-UHFFFAOYSA-N
Storage	-20°C

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