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Bis-sulfone-PEG2-Acid

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Category Bis-sulfone-PEGn-Acid
Catalog NO. BPG-3364
Product Name Bis-sulfone-PEG2-Acid
Molecular Formula C32H37NO10S2
Molecular Weight 659.77
Bis-sulfone-PEG2-Acid
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Product Information

Description Bis-Sulfone-PEG2-acid is a PEG linker with a sulfone and acid end group. The sulfone group can be conjugated with thiol groups of proteins. The terminal carboxylic acid can react with primary amines in the presence of activators such as EDC and HATU to form stable amide bonds. The hydrophilic PEG chain increases the water solubility of the compound in aqueous media.
Synonyms 3-(2-(2-(4-(3-tosyl-2-(tosylmethyl)propanoyl)benzamido)ethoxy)ethoxy)propanoic acid
IUPAC Name 3-[2-[2-[[4-[3-(4-methylphenyl)sulfonyl-2-[(4-methylphenyl)sulfonylmethyl]propanoyl]benzoyl]amino]ethoxy]ethoxy]propanoic acid
Canonical SMILES OC(CCOCCOCCNC(C1=CC=C(C=C1)C(C(CS(C2=CC=C(C=C2)C)(=O)=O)CS(C3=CC=C(C=C3)C)(=O)=O)=O)=O)=O
InChI InChI=1S/C32H37NO10S2/c1-23-3-11-28(12-4-23)44(38,39)21-27(22-45(40,41)29-13-5-24(2)6-14-29)31(36)25-7-9-26(10-8-25)32(37)33-16-18-43-20-19-42-17-15-30(34)35/h3-14,27H,15-22H2,1-2H3,(H,33,37)(H,34,35)
InChIKey IDSWXWTYYNVCGK-UHFFFAOYSA-N
Purity ≥95%
Storage Store at -20°C

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PEGylation of Peptides and Proteins

PEGylation of Peptides
and Proteins

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