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Bis-PEG2-NHS Ester

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Category Bis-PEGn-NHS ester
Catalog NO. BPG-3565
Product Name Bis-PEG2-NHS Ester
CAS 65869-63-8
Molecular Formula C16H20N2O10
Molecular Weight 400.34
Bis-PEG2-NHS Ester
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Product Information

Description Bis-PEG2-NHS ester is a non-cleavable 2-unit PEG linker that can be used to synthesize antibody-conjugated drugs (ADCs).
Synonyms Bis(2,5-dioxopyrrolidin-1-yl) 3,3'-(ethane-1,2-diylbis(oxy))dipropionate; Bis-PEG2-NHS; 2,5-Pyrrolidinedione, 1,1'-[1,2-ethanediylbis[oxy(1-oxo-3,1-propanediyl)oxy]]bis-; 1,1'-{1,2-Ethanediylbis[oxy(1-oxo-3,1-propanediyl)oxy]}di(2,5-pyrrolidinedione)
IUPAC Name (2,5-dioxopyrrolidin-1-yl) 3-[2-[3-(2,5-dioxopyrrolidin-1-yl)oxy-3-oxopropoxy]ethoxy]propanoate
Canonical SMILES C1CC(=O)N(C1=O)OC(=O)CCOCCOCCC(=O)ON2C(=O)CCC2=O
InChI InChI=1S/C16H20N2O10/c19-11-1-2-12(20)17(11)27-15(23)5-7-25-9-10-26-8-6-16(24)28-18-13(21)3-4-14(18)22/h1-10H2
InChIKey SORMJGWNAXHOFC-UHFFFAOYSA-N
Boiling Point 547.2±60.0°C (Predicted)
Purity ≥98%
Density 1.46±0.1 g/cm3 (Predicted)
Solubility Soluble in DMSO
Related CAS 123502-57-8 (polymer)
Appearance White Solid
Storage Store at 2-8°C

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PEGylation of Peptides and Proteins

PEGylation of Peptides
and Proteins

Reduce the Immunogenicity of Peptide/Protein Drugs

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