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Bis-PEG12-NHS ester

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Category Bis-PEGn-NHS ester
Catalog NO. BPG-1240
Product Name Bis-PEG12-NHS ester
Molecular Formula C36H60N2O20
Molecular Weight 840.87
Bis-PEG12-NHS ester
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Product Information

Description Bis-PEG12-NHS ester is a non-cleavable 12-unit PEG linker that can be used to synthesize antibody-conjugated drugs (ADCs).
Synonyms NHS-PEG12-NHS; Bis(2,5-dioxopyrrolidin-1-yl) 4,7,10,13,16,19,22,25,28,31,34,37-dodecaoxatetracontanedioate
IUPAC Name (2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[3-(2,5-dioxopyrrolidin-1-yl)oxy-3-oxopropoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoate
Canonical SMILES C1CC(=O)N(C1=O)OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)ON2C(=O)CCC2=O
InChI InChI=1S/C36H60N2O20/c39-31-1-2-32(40)37(31)57-35(43)5-7-45-9-11-47-13-15-49-17-19-51-21-23-53-25-27-55-29-30-56-28-26-54-24-22-52-20-18-50-16-14-48-12-10-46-8-6-36(44)58-38-33(41)3-4-34(38)42/h1-30H2
InChIKey ZLKOMOFBMCZXDH-UHFFFAOYSA-N
Purity ≥95%
Related CAS 123502-57-8 (polymer)
Appearance Pale Yellow or Colorless Oily Matter
Storage Store at 2-8°C

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PEGylation of Peptides and Proteins

PEGylation of Peptides
and Proteins

Reduce the Immunogenicity of Peptide/Protein Drugs

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PEG linkers For Drug

Improved Circulation Half-Life

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