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Bis(NHS)PEG5

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Category Bis-PEGn-NHS ester
Catalog NO. BPG-2300
Product Name Bis(NHS)PEG5
CAS 756526-03-1
Molecular Formula C22H32N2O13
Molecular Weight 532.50
Bis(NHS)PEG5
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Product Information

Description Bis(NHS)PEG5 is a non-cleavable 5-unit PEG linker that can be used to synthesize antibody-conjugated drugs (ADCs).
Synonyms Bis-PEG5-NHS ester; Bis(2,5-dioxopyrrolidin-1-yl) 4,7,10,13,16-pentaoxanonadecane-1,19-dioate; NHS-PEG5-NHS; Bis-dPEG(R)5-NHS ester; Bis(2,5-dioxopyrrolidin-1-yl) 4,7,10,13,16-pentaoxanonadecanedioate; Bis(3-PEG4)propionic acid N-hydroxysuccinimide diester; 1,1'-[(1,19-Dioxo-4,7,10,13,16-pentaoxanonadecane-1,19-diyl)bis(oxy)]di(2,5-pyrrolidinedione); 2,5-Pyrrolidinedione, 1,1'-[(1,19-dioxo-4,7,10,13,16-pentaoxanonadecane-1,19-diyl)bis(oxy)]bis-; α,ω-disuccinimidyl tetraethylene glycol
IUPAC Name (2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-[2-[3-(2,5-dioxopyrrolidin-1-yl)oxy-3-oxopropoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoate
Canonical SMILES C1CC(=O)N(C1=O)OC(=O)CCOCCOCCOCCOCCOCCC(=O)ON2C(=O)CCC2=O
InChI InChI=1S/C22H32N2O13/c25-17-1-2-18(26)23(17)36-21(29)5-7-31-9-11-33-13-15-35-16-14-34-12-10-32-8-6-22(30)37-24-19(27)3-4-20(24)28/h1-16H2
InChIKey FTYUGLBWKRXQBD-UHFFFAOYSA-N
Boiling Point 632.5±65.0°C at 760 mmHg
Purity 98%
Density 1.4±0.1 g/cm3
Solubility Soluble in DCM, DMF, DMSO
Related CAS 123502-57-8 (polymer)
Appearance Colorless to Yellow Clear Liquid to Cloudy Liquid
Storage Store at 2-8°C

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PEGylation of Peptides and Proteins

PEGylation of Peptides
and Proteins

Reduce the Immunogenicity of Peptide/Protein Drugs

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