Azido-PEG4-acetic Acid

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Category	Azido-PEGn-CH2COOH
Catalog NO.	BPG-3554
Product Name	Azido-PEG4-acetic Acid
CAS	201467-81-4
Molecular Formula	C10H19N3O6
Molecular Weight	277.27

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Description	N33-TEG-COOH is a PROTAC linker containing four polyethylene glycol (PEG) units. N33-TEG-COOH is a PEG derivative containing an azide group with a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond.
Synonyms	Azido-PEG4-CH2CO2H;Azido-PEG4-CH2COOH; N3-TEG-COOH; N3-PEG4-CH2COOH; 14-azido-3,6,9,12-tetraoxatetradecanoic acid; Acetic acid, 2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]-; 14-azido-3,6,9,12-tetraoxatetradecan-1-oic acid
IUPAC Name	2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]acetic acid
Canonical SMILES	C(COCCOCCOCCOCC(=O)O)N=[N+]=[N-]
InChI	InChI=1S/C10H19N3O6/c11-13-12-1-2-16-3-4-17-5-6-18-7-8-19-9-10(14)15/h1-9H2,(H,14,15)
InChIKey	YHTABJLSZLHRFV-UHFFFAOYSA-N
Purity	≥95%
Density	0.750-0.850 g/mL at 20°C
Solubility	Soluble in DMSO, Water
Appearance	Liquid
Storage	Store at 2-8°C
Exact Mass	277.12738533
LogP	-0.09954
Pictogram(s)	Irritant
Signal	Warning
Precautionary Statement Codes	P264, P264+P265, P280, P302+P352, P305+P351+P338, P321, P332+P317, P337+P317, and P362+P364

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