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Azido-PEG11-amine
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| Category | Small-molecule Heterobifunctional PEG |
| Catalog NO. | BPG-2358 |
| Product Name | Azido-PEG11-amine |
| CAS | 1800414-71-4 |
| Molecular Formula | C24H50N4O11 |
| Molecular Weight | 570.67 |
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| Description | Azido-PEG11-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It is also a non-cleavable 9 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
| Synonyms | 35-azido-3,6,9,12,15,18,21,24,27,30,33-undecaoxapentatriacontan-1-amine; 3,6,9,12,15,18,21,24,27,30,33-Undecaoxapentatriacontan-1-amine, 35-azido-; Azido-PEG11-NH2; N3-PEG11-CH2CH2NH2 |
| IUPAC Name | 2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanamine |
| Canonical SMILES | C(COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=N)N |
| InChI | InChI=1S/C24H51N4O11/c25-1-3-29-5-7-31-9-11-33-13-15-35-17-19-37-21-23-39-24-22-38-20-18-36-16-14-34-12-10-32-8-6-30-4-2-27-28-26/h26H,1-25H2/q+1 |
| InChIKey | XSNNFLVNOIPCFW-UHFFFAOYSA-N |
| Purity | >97% |
| Appearance | Colorless or Light Yellowish Liquid |
| Storage | Store at 2-8°C |
| Exact Mass | 570.34760842 |
| LogP | 0.59106 |
| Pictogram(s) | Irritant |
| Signal | Warning |
| Precautionary Statement Codes | P264, P264+P265, P280, P302+P352, P305+P351+P338, P321, P332+P317, P337+P317, and P362+P364 |
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Resources
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Technical Information
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- Polyethylene Glycol (PEG) Modifier Selection Guide
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Industry News
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- Lipid Classification and Drug Delivery Systems
- Lipid Formulations: Key Absorption-Enhancing Technologies in New Drug Development
- Lipid-Drug Conjugates (LDCs) for Nanoparticle Drug Delivery
- Liposome in Drug Delivery
- Overview of Liposome Preparation Process
- PEG in Pharmaceutical Preparations (I): Solvents, Lubricants, Adhesives and More
- PEG in Pharmaceutical Preparations (II): Stabilizers, Plasticizers and Modification Materials
- PEG Linkers in Antibody Drug Conjugates and PROTACs
- PEG-DSPE Block Copolymers and Their Derivatives
- PEGylated Drugs: Definition, Structure, Classification and Benefits
- PEGylated RGD Peptides: A Promising Tool for Targeted Drug Delivery
- Pharmacokinetics and Bioanalysis of PEGylated Drugs
- Polyethylene Glycol (PEG) Modified Targeting Nanomaterials
- Preparation Method of PEG Hydrogel
- The PROTAC Technology in Drug Development
- Vaccines: Definition, History, Ingredients, Types and Mechanism of Action
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- What are Lipid Nanoparticles and Their Applications?
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