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Azido-PEG1-NHS ester

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Category Azido-PEGn-NHS ester
Catalog NO. BPG-0868
Product Name Azido-PEG1-NHS ester
CAS 1807530-06-8
Molecular Formula C9H12N4O5
Molecular Weight 256.22
Azido-PEG1-NHS ester
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Product Information

Description Azido-PEG1-NHS ester is a PEG derivative containing an azide group and an NHS ester. The hydrophilic PEG spacer increases solubility in aqueous media. The azide group can react with alkyne, BCN, and DBCO via Click Chemistry to yield a stable triazole linkage. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
Synonyms N3-PEG1-CH2CH2COONHS; Propanoic acid, 3-(2-azidoethoxy)-, 2,5-dioxo-1-pyrrolidinyl ester; 1-{[3-(2-Azidoethoxy)propanoyl]oxy}-2,5-pyrrolidinedione; 2,5-Pyrrolidinedione, 1-[3-(2-azidoethoxy)-1-oxopropoxy]-
IUPAC Name (2,5-dioxopyrrolidin-1-yl) 3-(2-azidoethoxy)propanoate
Canonical SMILES C1CC(=O)N(C1=O)OC(=O)CCOCCN=[N+]=[N-]
InChI InChI=1S/C9H12N4O5/c10-12-11-4-6-17-5-3-9(16)18-13-7(14)1-2-8(13)15/h1-6H2
InChIKey MGKGKSFTIINDPY-UHFFFAOYSA-N
Purity ≥95%
Solubility Soluble in DCM, DMF, DMSO
Related CAS 1108750-59-9 (polymer)
Appearance Pale Yellow Oily Liquid
Storage Store at 2-8°C

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PEGylation of Peptides and Proteins

PEGylation of Peptides
and Proteins

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