Aminooxy-PEG10-Aminooxy

Name: Aminooxy-PEG10-Aminooxy
Brand: BOC Sciences
Rating: 5 (1 reviews)

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Category	Aminooxy-PEGn-Aminooxy
Catalog NO.	BPG-0785
Product Name	Aminooxy-PEG10-Aminooxy
Molecular Formula	C22H48N2O12
Molecular Weight	532.63

Aminooxy-PEG10-Aminooxy @(data.CAS != null ? $"| CAS " : "") - BOC Sciences

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Description	Aminooxy-PEG10-Aminooxy is a PEG derivative containing two aminooxy groups that can be used in bioconjugation. It reacts with an aldehyde to form an oxime bond. If a reductant is used, it will form a hydroxylamine linkage. PEG Linkers may be useful in the development of antibody drug conjugates and drug delivery methods.
Synonyms	Bis-aminooxy-PEG10; O,O'-(3,6,9,12,15,18,21,24,27,30-decaoxadotriacontane-1,32-diyl)bis(hydroxylamine)
IUPAC Name	O-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-aminooxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl]hydroxylamine
SMILES	C(COCCOCCOCCOCCOCCON)OCCOCCOCCOCCOCCON
InChI	InChI=1S/C22H48N2O12/c23-35-21-19-33-17-15-31-13-11-29-9-7-27-5-3-25-1-2-26-4-6-28-8-10-30-12-14-32-16-18-34-20-22-36-24/h1-24H2
InChIKey	YVWYHEIBQRXHII-UHFFFAOYSA-N
Purity	≥95%
Appearance	Pale Yellow or Colorless Oily Matter
Storage	Store at 2-8°C

Aminooxy-PEG10-Aminooxy, a bi-functional polyethylene glycol (PEG) derivative, finds diverse applications in biochemical and biomedical fields. Here are four key applications of Aminooxy-PEG10-Aminooxy presented with high perplexity and burstiness:

Bioconjugation: Integral to bioconjugation processes, Aminooxy-PEG10-Aminooxy plays a pivotal role in linking biomolecules like proteins, peptides, and antibodies. Its aminooxy groups exhibit facile reactivity with aldehyde-containing molecules, culminating in the formation of stable oxime bonds. This feature is paramount in crafting bioconjugates tailored for diagnostics, therapeutics, and targeted delivery systems, showcasing the versatility and significance of this compound.

Surface Modification: A valuable tool for surface modification, Aminooxy-PEG10-Aminooxy is instrumental in altering the surfaces of nanoparticles, biosensors, and medical devices. By introducing functional groups, this compound facilitates subsequent chemical modifications, thereby enhancing biocompatibility and functional attributes. The resultant enhancement in the performance and stability of biomedical devices and nanocarriers underscores the transformative potential of this compound in advancing biomedical applications.

Protein Cross-Linking: Within the realm of protein chemistry, Aminooxy-PEG10-Aminooxy serves as a cornerstone for cross-linking proteins to form stable conjugates with diverse applications, including enzyme immobilization and protein-protein interaction studies. The robust and specific linkage provided by this compound ensures minimal perturbation to protein function, highlighting its utility in creating stable protein conjugates for a myriad of scientific and biomedical endeavors.

Drug Delivery: In the arena of advanced drug delivery systems, Aminooxy-PEG10-Aminooxy emerges as a key player, facilitating the conjugation of therapeutic agents to PEG molecules for enhanced drug solubility and stability. This conjugation strategy enables controlled and targeted drug release, consequently boosting drug efficacy while minimizing adverse side effects. The application of Aminooxy-PEG10-Aminooxy in drug delivery underscores its potential to revolutionize therapeutic interventions and elevate treatment outcomes.

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