| Category | Amino-PEGn-COOH |
| Molecular Formula | C15H31NO8 |
| Molecular Weight | 353.41 |
| Appearance | Solid |
| Shipping | Room temperature, or blue ice upon request. |
| Storage | Store at -20 °C, keep in dry and avoid sunlight. |
Amino-PEG6-propionic acid
4.5
Amino-PEG6-propionic acid is a medium-length PEG linker for ADCs, balancing hydrophilicity and flexibility to optimize drug-antibody conjugation and therapeutic delivery.
Structure of 905954-28-1
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- Specification
- Key Product Attributes
- Reaction & Conjugation Properties
| Synonyms | 1-Amino-3,6,9,12,15,18-hexaoxahenicosan-21-oic acid; Amino-PEG6-acid |
| IUPACName | 3-[2-[2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid |
| CanonicalSMILES | C(COCCOCCOCCOCCOCCOCCN)C(=O)O |
| InChI | InChI=1S/C15H31NO8/c16-2-4-20-6-8-22-10-12-24-14-13-23-11-9-21-7-5-19-3-1-15(17)18/h1-14,16H2,(H,17,18) |
| InChIKey | PVRGRRPCHFTMMD-UHFFFAOYSA-N |
| BoilingPoint | 481.0±45.0 °C at 760 mmHg |
| Purity | >98.0% |
| Density | 1.1±0.1 g/cm3 |
| Solubility | 10 mm in DMSO |
| RelatedCAS | 1818294-41-5 (polymer) 196936-04-6 (polymer) |
| ShelfLife | ≥ 2 years |
| LogP | 0.21970 |
| Pictogram | Irritant |
| Signal | Warning |
| PrecautionaryStatementCodes | P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 |
| PEGType | Discrete PEG Linker |
| PEGArchitecture | Linear |
| Functionality | Heterobifunctional |
| ReactiveToward | Activated Carboxyls / Activated Esters; Primary Amines (after activation) |
| ReactionChemistry | Amide Coupling; Carbodiimide-Mediated Amide Coupling (EDC/NHS) |
| BiomoleculeCompatibility | Proteins / Antibodies; Peptides; Carboxyl-Modified Oligonucleotides; Amine-Modified Oligonucleotides |
| ResearchUse | Carboxyl-to-Amine Coupling after Activation; Amide Bond Formation |
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