Amino-PEG6-alcohol
* Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Category | Small-molecule Heterobifunctional PEG |
Catalog NO. | BPG-1886 |
Product Name | Amino-PEG6-alcohol |
CAS | 39160-70-8 |
Molecular Formula | C12H27NO6 |
Molecular Weight | 281.35 |
- Scheme Design
- Custom Synthesis
- cGMP Manufacturing
- Quality Assurance
- Product Information
- Application
- References
- Documents
- Reviews
Description | Amino-PEG6-OH is a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
Synonyms | 17-Amino-3,6,9,12,15-pentaoxaheptadecan-1-ol; H2N-PEG6-OH; 1-Aminohexaethylene Glycol |
IUPAC Name | 2-[2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethanol |
Canonical SMILES | C(COCCOCCOCCOCCOCCO)N |
InChI | InChI=1S/C12H27NO6/c13-1-3-15-5-7-17-9-11-19-12-10-18-8-6-16-4-2-14/h14H,1-13H2 |
InChIKey | ICUIZKMGHRMMDZ-UHFFFAOYSA-N |
Boiling Point | 388.0±37.0 °C at 760 mmHg |
Flash Point | 188.5±26.5 °C |
Purity | ≥95% |
Density | 1.1±0.1 g/cm3 |
Solubility | Soluble in DMSO (10 mm) |
Related CAS | 933789-97-0 (polymer) |
Appearance | Pale Yellow or Colorless Oily Matter |
Storage | Store at 2-8°C |
Exact Mass | 281.18383758 |
Vapor Pressure | 0.0±2.0 mmHg at 25°C |
LogP | -2.80 |
Pictogram(s) | Irritant |
Signal | Warning |
Precautionary Statement Codes | P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 |
Amino-PEG6-alcohol, a polyethylene glycol derivative, has numerous applications in the fields of biotechnology and pharmaceuticals. Here are some key applications of Amino-PEG6-alcohol: Drug Delivery Systems: Amino-PEG6-alcohol is often used to improve the solubility and stability of pharmaceutical compounds. By conjugating drugs with PEG, the circulation time in the bloodstream is increased, enhancing the bioavailability and therapeutic efficacy. This can lead to more effective treatments with reduced dosing frequency. Protein Modification: In biotechnology, Amino-PEG6-alcohol is used to modify proteins and peptides to improve their pharmacokinetic properties. The PEGylation process can reduce immunogenicity and increase the half-life of therapeutic proteins. This modification is crucial for the development of biologics and peptide-based drugs. Diagnostics: Amino-PEG6-alcohol finds application in the development of diagnostic assays and imaging agents. By attaching PEG chains to antibodies or other biomolecules, the stability and functionality of diagnostic reagents can be enhanced. This results in more accurate and reliable diagnostic tests and imaging techniques. Bioconjugation: Amino-PEG6-alcohol is extensively used in bioconjugation techniques for attaching various biomolecules, such as enzymes, antibodies, and nucleic acids. The PEG linker provides flexibility and reduces steric hindrance, facilitating the formation of stable conjugates. This is essential for creating multifunctional bioconjugates for research and therapeutic applications. |
Reviews
If you have any suggestions or comments about mPEG-Br, please submit a review immediately.
Why BOC Sciences?
-
Large Stock
More than 2000+ products in inventory
-
Global Delivery
Warehouses in multiple cities to ensure fast delivery
-
mg to kg
Multi specification for academic research and industrial production
-
24/7 Technical Support
Strict process parameter control to ensure product quality
Products
- Lipids
- PEG Derivatives by Structure
-
PEG Derivatives by Functional Group
- Acrylate/Acrylamide/Methacrylate PEG
- Aldehyde (Ald/CHO)PEG
- Alkyne PEG
- Amino PEG, PEG amine(-NH2)
- Azide PEG, Azido PEG(-N3)
- Biotin PEG
- Boc/Fmoc protected amine PEG
- Carboxylic Acid(-COOH) PEG
- Cholesterol PEG
- DBCO PEG
- DNP PEG
- DSPE PEG
- Epoxide glycidyl ether PEG
- FITC PEG
- Folate PEG
- Halide (chloride, bromide) PEG
- Hydrazide PEG
- Hydroxyl(-OH) PEG
- Maleimide(-MAL) PEG
- NHS ester PEG
- Nitrophenyl carbonate (NPC) PEG
- Norbornene PEG
- Olefin/Alkene/Vinyl PEG
- Orthopyridyl disulfide (OPSS) PEG
- Phosphate PEG
- Rhodamine PEG
- SCM PEG
- Silane PEG
- SPDP PEG
- Sulfonate (tosyl, mesyl, tresyl) PEG
- tert-Butyl protected carboxylate PEG
- Thiol(-SH) PEG
- Vinylsulfone PEG
- PEG Copolymers
-
PEG Raw Materials
- Small-molecule Polyethylene Glycol
- Polyethylene Glycol 1000
- Polyethylene Glycol 10000
- Polyethylene Glycol 1500
- Polyethylene Glycol 200
- Polyethylene Glycol 2000
- Polyethylene Glycol 20000
- Polyethylene Glycol 400
- Polyethylene Glycol 4000
- Polyethylene Glycol 600
- Polyethylene Glycol 6000
- Polyethylene Glycol 800
- Polyethylene Glycol 8000
Resources
-
Technical Information
- Aqueous Two-Phase System (ATPS) Technique
- Capillary Electrophoresis (CE) Technique
- Enzyme-linked immunosorbent assay (ELISA) Technique
- High performance liquid chromatography (HPLC) Technique
- How to Perform Polyethylene Glycol (PEG) Modification?
- Hydrophobic Interaction Chromatography (HIC) Technique
- Introduction of Polyethylene Glycol (PEG)
- Ion Exchange Chromatography (IEX) Technique
- PEG for Chemical Synthesis
- PEG for Cosmetic Application
- PEG for Drug Delivery
- PEG for Imaging Diagnosis
- PEG for Pharmaceutical Preparation
- PEG for Tissue Engineering
- PEG Purification Techniques of Plasmid DNA
- PEGylated Protein Purification Techniques
- Polyethylene Glycol (PEG) Modifier Selection Guide
- Radiolabeling Technique
- SDS-PAGE Technique
- Size Exclusion Chromatography (SEC) Technique
- Ultrafiltration Technique
-
Industry News
- Applications of PEG-DSPE: Drug Carriers and Drug Delivery
- Applications of Polyethylene Glycol (PEG) as Medical Devices
- Cholesterol: Definition, Structure, Synthesis, Types and Functions
- Classification of Lipid-Based Vaccine Adjuvants
- FDA approved PEGylated Products
- FDA-Approved Antibody-Drug Conjugates up to 2024
- How are Liposomes Different from Micelles?
- How Lipid Nanoparticles (LNPs) Deliver RNA Drugs?
- Hyaluronic Acid & PEGylated Hyaluronic Acid
- Ionizable Lipids for RNA Delivery
- Lipid Classification and Drug Delivery Systems
- Lipid Formulations: Key Absorption-Enhancing Technologies in New Drug Development
- Lipid-Drug Conjugates (LDCs) for Nanoparticle Drug Delivery
- Liposome in Drug Delivery
- Overview of Liposome Preparation Process
- PEG in Pharmaceutical Preparations (I): Solvents, Lubricants, Adhesives and More
- PEG in Pharmaceutical Preparations (II): Stabilizers, Plasticizers and Modification Materials
- PEG Linkers in Antibody Drug Conjugates and PROTACs
- PEG-DSPE Block Copolymers and Their Derivatives
- PEGylated Drugs: Definition, Structure, Classification and Benefits
- PEGylated RGD Peptides: A Promising Tool for Targeted Drug Delivery
- Pharmacokinetics and Bioanalysis of PEGylated Drugs
- Polyethylene Glycol (PEG) Modified Targeting Nanomaterials
- Preparation Method of PEG Hydrogel
- The PROTAC Technology in Drug Development
- Vaccines: Definition, History, Ingredients, Types and Mechanism of Action
- What are Lipid Excipients and Their Applications?
- What are Lipid Nanoparticles and Their Applications?
- What are Lipid-Drug Conjugates (LDCs)?
- What are Lipids?
- What are Monodispersed and Polydispersed PEGs?
- What are PEG Lipids?
- What are Phospholipids?
- What are Sterols? - Definition, Structure, Function, Examples and Uses
- What is Biotinylation and Biotinylated PEG?
- What is Click Chemistry?
- What is Hydrogel?
- What is Methoxy Polyethylene Glycol (mPEG)?
- What is Nanogels and Its Applications?
- What is the Formulation of Lipid Nanoparticles (LNPs)?
Our Feature
BOC Sciences supplies a unique variety of PEG derivatives and functional PEG polymers. Our products offer the most diverse collection of reactivity, ready-to-use functionality, and molecular weight options that you will not find anywhere else.
PEGylation of Peptides
and Proteins
Reduce the Immunogenicity of Peptide/Protein Drugs
Learn More
APPLICATIONS
PEG linkers For Drug
Improved Circulation Half-Life
Learn More
Have Customer Reviewed On Us?
Chat With Us