Amino-PEG3-alcohol
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Category | Small-molecule Heterobifunctional PEG |
Catalog NO. | BPG-1709 |
Product Name | Amino-PEG3-alcohol |
CAS | 6338-55-2 |
Molecular Formula | C6H15NO3 |
Molecular Weight | 149.19 |
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Description | 2-[2-(2-Aminoethoxy)ethoxy]ethanol (CAS# 6338-55-2) is a useful research chemical compound. |
Synonyms | 2-[2-(2-aminoethoxy)ethoxy]ethanol; 2-[2-(2-aminoethoxy)ethoxy]ethanol |
IUPAC Name | 2-[2-(2-aminoethoxy)ethoxy]ethanol |
Canonical SMILES | C(COCCOCCO)N |
InChI | InChI=1S/C6H15NO3/c7-1-3-9-5-6-10-4-2-8/h8H,1-7H2 |
InChIKey | ASDQMECUMYIVBG-UHFFFAOYSA-N |
Boiling Point | 253.8 °C at 760 mmHg |
Purity | >98% |
Density | 1.054 g/cm3 |
Solubility | In DMSO: 100 mg/mL (670.29 mM; Need ultrasonic) |
Related CAS | 933789-97-0 (polymer) |
Appearance | Colorless Liquid |
Storage | 4°C, protect from light; In solvent, -80°C, 6 months; -20°C, 1 month (protect from light) |
Exact Mass | 149.10519334 |
LogP | -0.32910 |
Pictogram(s) | Corrosive |
Signal | Danger |
Precautionary Statement Codes | P260, P264, P280, P301+P330+P331, P302+P361+P354, P304+P340, P305+P354+P338, P316, P321, P363, P405, and P501 |
Amino-PEG3-alcohol, a versatile linker molecule, finds diverse applications in bioconjugation and drug delivery systems. Here are four key applications presented with high perplexity and burstiness: Drug Conjugation: Utilizing Amino-PEG3-alcohol, researchers attach drugs to carrier molecules, like antibodies or nanoparticles, enhancing solubility and stability. This coupling ensures targeted drug delivery to specific cells, decreasing off-target effects and enhancing therapeutic efficacy. Furthermore, conjugation with Amino-PEG3-alcohol can extend the half-life of therapeutics in circulation, optimizing treatment outcomes. Targeted Drug Delivery: The versatility of Amino-PEG3-alcohol in linking biologically active compounds to targeting moieties, such as ligands or antibodies, is pivotal in crafting precise drug delivery systems. This targeted approach directs therapeutic agents specifically to afflicted areas like tumors or inflamed tissues, maximizing treatment effectiveness while minimizing adverse effects. Surface Modification: Amino-PEG3-alcohol serves a crucial role in modifying the surfaces of diverse biomaterials, including nanoparticles, medical devices, and biosensors. By binding to these surfaces, it enhances biocompatibility, diminishes protein adsorption, and decreases immune recognition. Such surface modification is indispensable for advancing biomedical devices and diagnostic instruments. Bioconjugation Research: In laboratory investigations, Amino-PEG3-alcohol emerges as a key reagent for conjugating biomolecules, such as proteins, peptides, and nucleic acids. This enables the creation of multifunctional complexes employed in various assays, like immunoassays and molecular diagnostics. Through such conjugation processes, researchers gain deeper insights into protein interactions and cellular pathways, enriching our understanding of biological mechanisms. |
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Technical Information
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PEGylation of Peptides
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Reduce the Immunogenicity of Peptide/Protein Drugs
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