Acs-PEG7-propargyl

Name: Acs-PEG7-propargyl
Brand: BOC Sciences
Rating: 5 (1 reviews)

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Category	AcS-PEGn-propargyl
Catalog NO.	BPG-0079
Product Name	Acs-PEG7-propargyl
Molecular Formula	C19H34O8S
Molecular Weight	422.52

Acs-PEG7-propargyl @(data.CAS != null ? $"| CAS " : "") - BOC Sciences

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Description	Acs-PEG7-propargyl is a PEG linker containing a sulfur acetyl group and a propargyl moiety. The sulfur acetyl group can be deprotected to produce a thiol compound. The propargyl group can react with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage. The hydrophilic PEG linker increases the water solubility of the compounds in the aqueous media.
Synonyms	S-acetyl-PEG7-Propargyl; Acetylthio-PEG7-Alkyne; S-acetyl-PEG7-alkyne; S-(3,6,9,12,15,18,21-heptaoxatetracos-23-yn-1-yl) ethanethioate
IUPAC Name	S-[2-[2-[2-[2-[2-[2-(2-prop-2-ynoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl] ethanethioate
SMILES	CC(SCCOCCOCCOCCOCCOCCOCCOCC#C)=O
InChI	InChI=1S/C19H34O8S/c1-3-4-21-5-6-22-7-8-23-9-10-24-11-12-25-13-14-26-15-16-27-17-18-28-19(2)20/h1H,4-18H2,2H3
InChIKey	WSKKJIMOLRVQMR-UHFFFAOYSA-N
Purity	≥95%
Storage	Store at 2-8°C

Acs-PEG7-propargyl, a versatile compound prized in the realms of chemical and biological research for its exceptional properties, serves a multitude of functions. Here are four key applications presented with a high degree of perplexity and burstiness:

Bioconjugation: Harnessing the potential of Acs-PEG7-propargyl in bioconjugation facilitates the fusion of diverse biomolecules, ranging from proteins to nucleic acids and peptides. With its propargyl group enabling click chemistry interactions with azide-containing counterparts, researchers can establish robust conjugates. This exploration unlocks the intricacies of biomolecular interactions and fosters the development of targeted delivery systems, unveiling new horizons in molecular connectivity.

Surface Modification: Researchers leverage Acs-PEG7-propargyl to augment the surfaces of nanoparticles and biomaterials, enhancing their biocompatibility and functionality. The PEG spacer serves as a crucial component in providing steric stabilization, suppressing nonspecific interactions, and amplifying the stability and performance of modified surfaces. These adaptations play a pivotal role in biomedical fields, propelling advancements in drug delivery and tissue engineering with finesse.

Drug Delivery Systems: In the pharmaceutical domain, Acs-PEG7-propargyl emerges as a cornerstone in crafting intricate drug delivery systems. By linking therapeutic agents with this compound, scientists can orchestrate controlled release mechanisms and target drug delivery specifically to desired tissues or cells. This precision not only amplifies treatment efficacy but also minimizes undesirable side effects, guiding drug delivery into a realm of personalized precision.

Chemical Probes and Sensors: Acs-PEG7-propargyl carves a niche for itself in the creation of chemical probes and biosensors tailored for the detection and quantification of biological targets. Its chemical reactivity presents opportunities for attaching fluorescent dyes and other detection moieties, enabling sensitive and specific analyte detection within complex samples. These tools emerge as indispensable assets in diagnostics and high-throughput screening within the dynamic landscape of biomedical research.

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