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3,6,9-Trioxaundecanedioic acid

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Category	Small-molecule Homobifunctional PEG
Catalog NO.	BPG-1775
Product Name	3,6,9-Trioxaundecanedioic acid
CAS	13887-98-4
Molecular Formula	C8H14O7
Molecular Weight	222.19

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Product Information

Description	3,6,9-Trioxaundecanedioic Acid is a polyethylene glycol (PEG)-based PROTAC linker. 3,6,9-Trioxaundecanedioic Acid can be used in the synthesis of a series of PROTACs.
Synonyms	COOH-CH2-PEG3-CH2-COOH; COOH-CH2-PEG2-CH2-COOH; 2,2'-((Oxybis(ethane-2,1-diyl))bis(oxy))diacetic acid; O,O'-Oxydiethylene-diglycolic acid; Acetic acid, 2,2'-[oxybis(2,1-ethanediyloxy)]bis-; 2,2'-(2,2'-Oxybis(ethane-2,1-diyl)bis(oxy))diacetic acid
IUPAC Name	2-[2-[2-(carboxymethoxy)ethoxy]ethoxy]acetic acid
Canonical SMILES	C(COCC(=O)O)OCCOCC(=O)O
InChI	InChI=1S/C8H14O7/c9-7(10)5-14-3-1-13-2-4-15-6-8(11)12/h1-6H2,(H,9,10)(H,11,12)
InChIKey	HJZZQNLKBWJYPD-UHFFFAOYSA-N
Boiling Point	443.7±30.0°C at 760 mmHg
Flash Point	178.3°C
Purity	>95%
Density	1.3 g/mL at 20°C
Solubility	Soluble in DCM, DMF, DMSO, Water
Appearance	Liquid
Storage	Store at 2-8°C
Refractive Index	n20/D 1.470(lit.)
Pictogram(s)	Corrosive
Signal	Danger
Precautionary Statement Codes	P264+P265, P280, P305+P354+P338, and P317

3,6,9-Trioxaundecanedioic acid, an organic compound with diverse industrial and research applications, serves as a versatile building block in various fields. Below are its key applications explained with high perplexity and burstiness:

Polymer Synthesis: Integral to creating polyesters and polyamides, 3,6,9-Trioxaundecanedioic acid plays a crucial role in crafting polymers known for their flexibility, strength, and biocompatibility. These properties make them ideal for applications ranging from medical devices to environmentally-friendly packaging materials. Incorporating 369-Trioxaundecanedioic acid enhances the thermal and mechanical characteristics of these polymers, adding a layer of resilience and adaptability.

Coating and Adhesives: Leveraging its unique chemical structure, 3,6,9-Trioxaundecanedioic acid finds utility in formulating specialty coatings and adhesives. Coatings infused with this compound exhibit heightened stability and resilience to environmental degradation. In the realm of adhesives, it contributes to superior bonding strength and durability, finding applications across consumer products and industrial settings where performance is paramount.

Biodegradable Plastics: With a focus on sustainability, polymers derived from 3,6,9-Trioxaundecanedioic acid offer a pathway to eco-friendly plastics that are easily biodegradable. These materials break down more efficiently compared to their petroleum-based counterparts, reducing their environmental footprint. From disposable items to agricultural films and packaging materials, these biodegradable plastics play a crucial role in fostering a greener, more sustainable future.

Pharmaceutical Industry: Within the pharmaceutical sector, 3,6,9-Trioxaundecanedioic acid serves as a key precursor in synthesizing drug delivery systems. By aiding in creating polymer-based carriers, it enhances the solubility and bioavailability of drugs, improving their efficacy. Moreover, this acid facilitates the development of prodrugs, acting as a crucial linker that can be cleaved under specific physiological conditions to release the active drug molecule, paving the way for advanced drug delivery methods.

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