3,4-Dibromo-Mal-amido-PEG4-azide

Name: 3,4-Dibromo-Mal-amido-PEG4-azide
Brand: BOC Sciences
Rating: 5 (1 reviews)

Cat No.: BPG-4376

Purity: 0.95

4.5

3,4-Dibromo-Mal-amido-PEG4-azide is a PEG linker featuring a dibromomaleimide and an azide. The unsaturated dibromo motif is a covalent ligand for thiol groups, and may be used to label cysteine residues in proteins. The presence of two leaving groups on this molecule allows this linker to bind two thiols at a time. Meanwhile, the azide is a click chemistry handle that can readily react with terminal alkynes and strained cyclooctynes like BCN or DBCO.

Category	Small-molecule Maleimide PEG
Molecular Formula	C16H23Br2N5O7
Molecular Weight	557.2
Shipping	Ambient temperature
Storage	-20°C

Structure of 3,4-Dibromo-Mal-amido-PEG4-azide

Ordering Information

*For research and manufacturing use only. We do not sell to patients.

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Specification
Key Product Attributes
Reaction & Conjugation Properties

Purity

0.95

PEGType	Discrete PEG Linker
PEGArchitecture	Linear
Functionality	Heterobifunctional

ReactiveToward	Thiols; Terminal Alkynes; Strained Alkynes (DBCO/BCN)
ReactionChemistry	Maleimide-Thiol Conjugation; CuAAC Click Chemistry; SPAAC Click Chemistry
BiomoleculeCompatibility	Thiol-Bearing Proteins / Antibodies; Cysteine-Containing Peptides; Thiol-Modified Oligonucleotides; Click-Handle-Modified Proteins / Peptides; Click-Handle-Modified Antibodies; Click-Handle-Modified Oligonucleotides; Small Molecules / Probes
ResearchUse	Copper-Free Azide–Cyclooctyne Ligation; Copper-Catalyzed Azide–Alkyne Ligation; Thiol-Selective Biomolecule Conjugation