Azido-PEG4-amine
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| Category | Small-molecule Heterobifunctional PEG |
| Catalog NO. | BPG-1849 |
| Product Name | Azido-PEG4-amine |
| CAS | 951671-92-4 |
| Molecular Formula | C10H22N4O4 |
| Molecular Weight | 262.31 |
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| Description | N3-PEG4-C2-NH2 is a polyethylene glycol (PEG)-based PROTAC linker. N3-PEG4-C2-NH2 can be used in the synthesis of a series of PROTACs. N3-PEG4-C2-NH2 is a PEG derivative containing an amino group with an azide group. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. |
| Synonyms | 14-Azido-3,6,9,12-tetraoxatetradecan-1-amine; O-(2-Aminoethyl)-O'-(2-azidoethyl)triethylene Glycol; N3-PEG4-C2-NH2; N3-PEG4-CH2CH2NH2; 14-Amino-3,6,9,12-tetraoxatetradecanyl Azide; 1-Amino-14-azido-3,6,9,12-tetraoxatetradecane |
| IUPAC Name | 2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]ethanamine |
| Canonical SMILES | C(COCCOCCOCCOCCN=[N+]=[N-])N |
| InChI | InChI=1S/C10H22N4O4/c11-1-3-15-5-7-17-9-10-18-8-6-16-4-2-13-14-12/h1-11H2 |
| InChIKey | ZMBGKXBIVYXREN-UHFFFAOYSA-N |
| Purity | ≥95% |
| Density | 1.10 g/mL |
| Solubility | Soluble in DCM, DMF, DMSO, Water |
| Appearance | Colorless to Light Yellow to Light Orange Liquid |
| Storage | Store at 2-8°C |
| Exact Mass | 262.16410520 |
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Technical Information
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Industry News
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- PEG-DSPE Block Copolymers and Their Derivatives
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- Polyethylene Glycol (PEG) Modified Targeting Nanomaterials
- Preparation Method of PEG Hydrogel
- The PROTAC Technology in Drug Development
- What are Biotinylation and Biotinylated PEG?
- What are Lipid Excipients and Their Applications?
- What are Lipid Nanoparticles and Their Applications?
- What are Lipid-Drug Conjugates (LDCs)?
- What are Lipids?
- What are Monodispersed and Polydispersed PEGs?
- What are PEG Lipids?
- What are Phospholipids?
- What is Click Chemistry?
- What is Hydrogel?
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