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Tos-PEG5-THP

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Category	Tos-PEGn-THP
Catalog NO.	BPG-3470
Product Name	Tos-PEG5-THP
CAS	1549752-65-9
Molecular Formula	C22H36O9S
Molecular Weight	476.58

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Description	Tos-PEG5-THP is a PEG linker with a tosyl moiety and THP protecting group. It is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. The hydrophilic PEG linker increases the water solubility of the compound in aqueous media. THP is an alcohol protection group that can be removed under acidic conditions. Tosyl is an excellent leaving group for nucleophilic substitution reaction.
Synonyms	2-((3-tosyl-3γ3,4,7,10,13-pentaoxapentadecan-15-yl)oxy)tetrahydro-2H-pyran
IUPAC Name	2-[2-[2-[2-[2-(oxan-2-yloxy)ethoxy]ethoxy]ethoxy]ethoxy]ethyl 4-methylbenzenesulfonate
Canonical SMILES	O=S(C1=CC=C(C)C=C1)(OCCOCCOCCOCCOCCOC2OCCCC2)=O
InChI	InChI=1S/C22H36O9S/c1-20-5-7-21(8-6-20)32(23,24)31-19-17-28-15-13-26-11-10-25-12-14-27-16-18-30-22-4-2-3-9-29-22/h5-8,22H,2-4,9-19H2,1H3
InChIKey	QWYSLDAOPKGABA-UHFFFAOYSA-N
Purity	≥95%
Storage	Store at 2-8°C for short term (days to weeks) or -20°C for long term (months to years)

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