Tos-PEG5-O-CH2COOH
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| Category | Tos-PEGn-CH2COOH |
| Catalog NO. | BPG-3435 |
| Product Name | Tos-PEG5-O-CH2COOH |
| CAS | 1011301-34-0 |
| Molecular Formula | C19H30O10S |
| Molecular Weight | 450.50 |
- Scheme Design
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| Description | Tos-PEG5-O-CH2COOH is a PEG linker containing a tosyl group and a terminal carboxylic acid. The tosyl group is a very good leaving group for nucleophilic substitution reactions. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media. |
| Synonyms | Tos-PEG6-CH2COOH; Tos-PEG5-CH2COOH; 3,6,9,12,15-Pentaoxaheptadecanoic acid, 17-[[(4-methylphenyl)sulfonyl]oxy]-; 17-(tosyloxy)-3,6,9,12,15-pentaoxaheptadecanoic acid |
| IUPAC Name | 2-[2-[2-[2-[2-[2-(4-methylphenyl)sulfonyloxyethoxy]ethoxy]ethoxy]ethoxy]ethoxy]acetic acid |
| Canonical SMILES | CC1=CC=C(S(=O)(OCCOCCOCCOCCOCCOCC(O)=O)=O)C=C1 |
| InChI | InChI=1S/C19H30O10S/c1-17-2-4-18(5-3-17)30(22,23)29-15-14-27-11-10-25-7-6-24-8-9-26-12-13-28-16-19(20)21/h2-5H,6-16H2,1H3,(H,20,21) |
| InChIKey | JTCNCVWXPKDEKZ-UHFFFAOYSA-N |
| Purity | ≥95% |
| Storage | Store at 2-8°C |
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