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Tos-PEG4-O-CH2COOH

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Category Tos-PEGn-CH2COOH
Catalog NO. BPG-3433
Product Name Tos-PEG4-O-CH2COOH
CAS 2028284-73-1
Molecular Formula C17H26O9S
Molecular Weight 406.45
Tos-PEG4-O-CH2COOH
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Product Information

Description Tos-PEG4-O-CH2COOH is a PEG linker containing a tosyl group and a terminal carboxylic acid. The tosyl group is a very good leaving group for nucleophilic substitution reactions. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media.
Synonyms 14-(Tosyloxy)-3,6,9,12-tetraoxatetradecanoic acid; Tos-PEG5-CH2CO2H; Tos-PEG5-CH2COOH; Tos-PEG4-CH2COOH; Acetic acid, 2-[2-[2-[2-[2-[[(4-methylphenyl)sulfonyl]oxy]ethoxy]ethoxy]ethoxy]ethoxy]-; 14-{[(4-Methylphenyl)sulfonyl]oxy}-3,6,9,12-tetraoxatetradecan-1-oic acid; 3,6,9,12-Tetraoxatetradecan-1-oic acid, 14-[[(4-methylphenyl)sulfonyl]oxy]-
IUPAC Name 2-[2-[2-[2-[2-(4-methylphenyl)sulfonyloxyethoxy]ethoxy]ethoxy]ethoxy]acetic acid
Canonical SMILES CC1=CC=C(S(=O)(OCCOCCOCCOCCOCC(O)=O)=O)C=C1
InChI InChI=1S/C17H26O9S/c1-15-2-4-16(5-3-15)27(20,21)26-13-12-24-9-8-22-6-7-23-10-11-25-14-17(18)19/h2-5H,6-14H2,1H3,(H,18,19)
InChIKey MTBIBZOLTXFDIU-UHFFFAOYSA-N
Boiling Point 567.7±50.0°C (Predicted)
Purity ≥95%
Density 1.260±0.06 g/cm3 (Predicted)
Solubility Soluble in DMSO
Appearance Pale Yellow Oily Matter
Storage Store at 2-8°C for short term (days to weeks) or -20°C for long term (months to years)

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