Tos-PEG3-O-CH2COOH
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Category | Tos-PEGn-CH2COOH |
Catalog NO. | BPG-3436 |
Product Name | Tos-PEG3-O-CH2COOH |
CAS | 1581248-63-6 |
Molecular Formula | C15H22O8S |
Molecular Weight | 362.41 |
![Tos-PEG3-O-CH2COOH](https://resource.bocsci.com/structure/1581248-63-6.gif)
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Description | Tos-PEG3-O-CH2COOH is a PEG linker containing a tosyl group and a terminal carboxylic acid. The tosyl group is a very good leaving group for nucleophilic substitution reactions. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media. |
Synonyms | Tos-PEG4-CH2CO2H; Tos-PEG4-CH2COOH; Tos-PEG3-CH2COOH; 2-(2-(2-(2-(tosyloxy)ethoxy)ethoxy)ethoxy)acetic acid; {2-[2-(2-{[(4-Methylphenyl)sulfonyl]oxy}ethoxy)ethoxy]ethoxy}acetic acid; Acetic acid, 2-[2-[2-[2-[[(4-methylphenyl)sulfonyl]oxy]ethoxy]ethoxy]ethoxy]- |
IUPAC Name | 2-[2-[2-[2-(4-methylphenyl)sulfonyloxyethoxy]ethoxy]ethoxy]acetic acid |
Canonical SMILES | CC1=CC=C(S(=O)(OCCOCCOCCOCC(O)=O)=O)C=C1 |
InChI | InChI=1S/C15H22O8S/c1-13-2-4-14(5-3-13)24(18,19)23-11-10-21-7-6-20-8-9-22-12-15(16)17/h2-5H,6-12H2,1H3,(H,16,17) |
InChIKey | BOUJNGOUZPSTFF-UHFFFAOYSA-N |
Boiling Point | 539.9±45.0°C at 760 mmHg |
Purity | ≥95% |
Density | 1.3±0.1 g/cm3 |
Solubility | Soluble in DCM |
Storage | Store at 2-8°C |
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