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Tos-PEG3-O-CH2COOH

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Category Tos-PEGn-CH2COOH
Catalog NO. BPG-3436
Product Name Tos-PEG3-O-CH2COOH
CAS 1581248-63-6
Molecular Formula C15H22O8S
Molecular Weight 362.41
Tos-PEG3-O-CH2COOH
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Product Information

Description Tos-PEG3-O-CH2COOH is a PEG linker containing a tosyl group and a terminal carboxylic acid. The tosyl group is a very good leaving group for nucleophilic substitution reactions. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media.
Synonyms Tos-PEG4-CH2CO2H; Tos-PEG4-CH2COOH; Tos-PEG3-CH2COOH; 2-(2-(2-(2-(tosyloxy)ethoxy)ethoxy)ethoxy)acetic acid; {2-[2-(2-{[(4-Methylphenyl)sulfonyl]oxy}ethoxy)ethoxy]ethoxy}acetic acid; Acetic acid, 2-[2-[2-[2-[[(4-methylphenyl)sulfonyl]oxy]ethoxy]ethoxy]ethoxy]-
IUPAC Name 2-[2-[2-[2-(4-methylphenyl)sulfonyloxyethoxy]ethoxy]ethoxy]acetic acid
Canonical SMILES CC1=CC=C(S(=O)(OCCOCCOCCOCC(O)=O)=O)C=C1
InChI InChI=1S/C15H22O8S/c1-13-2-4-14(5-3-13)24(18,19)23-11-10-21-7-6-20-8-9-22-12-15(16)17/h2-5H,6-12H2,1H3,(H,16,17)
InChIKey BOUJNGOUZPSTFF-UHFFFAOYSA-N
Boiling Point 539.9±45.0°C at 760 mmHg
Purity ≥95%
Density 1.3±0.1 g/cm3
Solubility Soluble in DCM
Storage Store at 2-8°C

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