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Tos-PEG10-THP

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Category Tos-PEGn-THP
Catalog NO. BPG-3468
Product Name Tos-PEG10-THP
Molecular Formula C32H56O14S
Molecular Weight 696.85
Tos-PEG10-THP
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Product Information

Description Tos-PEG10-THP is a PEG linker with a tosyl moiety and THP protecting group. It is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. The hydrophilic PEG linker increases the water solubility of the compound in aqueous media. THP is an alcohol protection group that can be removed under acidic conditions. Tosyl is an excellent leaving group for nucleophilic substitution reaction.
Synonyms 2-((3-tosyl-3γ3,4,7,10,13,16,19,22,25,28-decaoxatriacontan-30-yl)oxy)tetrahydro-2H-pyran
IUPAC Name 2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(oxan-2-yloxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl 4-methylbenzenesulfonate
Canonical SMILES O=S(C1=CC=C(C)C=C1)(OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC2OCCCC2)=O
InChI InChI=1S/C32H56O14S/c1-30-5-7-31(8-6-30)47(33,34)46-29-27-43-25-23-41-21-19-39-17-15-37-13-11-35-10-12-36-14-16-38-18-20-40-22-24-42-26-28-45-32-4-2-3-9-44-32/h5-8,32H,2-4,9-29H2,1H3
InChIKey GBEZIPZVDADQPX-UHFFFAOYSA-N
Purity ≥95%
Storage Store at 2-8°C for short term (days to weeks) or -20°C for long term (months to years)

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