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Category Tos-PEGn-CH2COOH
Catalog NO. BPG-3437
Product Name Tos-PEG1-O-CH2COOH
CAS 2752009-40-6
Molecular Formula C11H14O6S
Molecular Weight 274.29
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Product Information

Description Tos-PEG1-O-CH2COOH is a PEG linker containing a tosyl group and a terminal carboxylic acid. The tosyl group is a very good leaving group for nucleophilic substitution reactions. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media.
Synonyms Tos-PEG2-CH2COOH; Tos-PEG1-CH2COOH; 2-(2-(Tosyloxy)ethoxy)acetic acid; (2-{[(4-Methylphenyl)sulfonyl]oxy}ethoxy)acetic acid; Acetic acid, 2-[2-[[(4-methylphenyl)sulfonyl]oxy]ethoxy]-
IUPAC Name 2-[2-(4-methylphenyl)sulfonyloxyethoxy]acetic acid
Canonical SMILES CC1=CC=C(S(=O)(OCCOCC(O)=O)=O)C=C1
InChI InChI=1S/C11H14O6S/c1-9-2-4-10(5-3-9)18(14,15)17-7-6-16-8-11(12)13/h2-5H,6-8H2,1H3,(H,12,13)
Boiling Point 487.7±30.0°C at 760 mmHg
Purity ≥95%
Density 1.3±0.1 g/cm3
Storage Store at 2-8°C


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