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THP-PEG4-alcohol
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| Category | HO-PEGn-THP |
| Catalog NO. | BPG-1878 |
| Product Name | THP-PEG4-alcohol |
| CAS | 128660-97-9 |
| Molecular Formula | C13H26O6 |
| Molecular Weight | 278.34 |
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| Description | THP-PEG4-OH is a polyethylene glycol (PEG)-based PROTAC linker. THP-PEG4-OH can be used in the synthesis of a series of PROTACs. |
| Synonyms | OH-PEG4-THP; THP-PEG5; HO-PEG4-THP; 2-(2-{2-[2-(Tetrahydropyran-2-yloxy)-ethoxy]-ethoxy}-ethoxy)-ethanol; 2-(2-(2-(2-((tetrahydro-2H-pyran-2-yl)oxy)ethoxy)ethoxy)ethoxy)ethan-1-ol; 2-[2-[2-[2-[(tetrahydro-2H-pyran-2-yl)oxy]ethoxy]ethoxy]-ethoxy]ethanol; Tetraethylene glycol mono-tetrahydropyran-2-yl ether; 2-[(11-Hydroxy-3,6,9-trioxaundecane-1-yl)oxy]tetrahydro-2H-pyran; Ethanol, 2-[2-[2-[2-[(tetrahydro-2H-pyran-2-yl)oxy]ethoxy]ethoxy]ethoxy]-; THP-PEG4-OH |
| IUPAC Name | 2-[2-[2-[2-(oxan-2-yloxy)ethoxy]ethoxy]ethoxy]ethanol |
| Canonical SMILES | C1CCOC(C1)OCCOCCOCCOCCO |
| InChI | InChI=1S/C13H26O6/c14-4-6-15-7-8-16-9-10-17-11-12-19-13-3-1-2-5-18-13/h13-14H,1-12H2 |
| InChIKey | XUTYVMRXVARJFT-UHFFFAOYSA-N |
| Boiling Point | 394.0±42.0 °C at 760 mmHg |
| Purity | ≥95% |
| Density | 1.1±0.1 g/cm3 |
| Related CAS | 92417-25-9 (polymer) 301295-36-3 (polymer) |
| Appearance | Colorless Oily Liquid |
| Storage | Store at 2-8°C |
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Resources
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Technical Information
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Industry News
- Applications of PEG-DSPE: Drug Carriers and Drug Delivery
- Applications of Polyethylene Glycol (PEG) as Medical Devices
- Cholesterol: Definition, Structure, Synthesis, Types and Functions
- Classification of Lipid-Based Vaccine Adjuvants
- FDA approved PEGylated Products
- FDA-Approved Antibody-Drug Conjugates up to 2024
- How are Liposomes Different from Micelles?
- How Lipid Nanoparticles (LNPs) Deliver RNA Drugs?
- Hyaluronic Acid & PEGylated Hyaluronic Acid
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- Lipid Formulations: Key Absorption-Enhancing Technologies in New Drug Development
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- Overview of Liposome Preparation Process
- PEG in Pharmaceutical Preparations (I): Solvents, Lubricants, Adhesives and More
- PEG in Pharmaceutical Preparations (II): Stabilizers, Plasticizers and Modification Materials
- PEG Linkers in Antibody Drug Conjugates and PROTACs
- PEG-DSPE Block Copolymers and Their Derivatives
- PEGylated Drugs: Definition, Structure, Classification and Benefits
- PEGylated RGD Peptides: A Promising Tool for Targeted Drug Delivery
- Pharmacokinetics and Bioanalysis of PEGylated Drugs
- Polyethylene Glycol (PEG) Modified Targeting Nanomaterials
- Preparation Method of PEG Hydrogel
- The PROTAC Technology in Drug Development
- Vaccines: Definition, History, Ingredients, Types and Mechanism of Action
- What are Lipid Excipients and Their Applications?
- What are Lipid Nanoparticles and Their Applications?
- What are Lipid-Drug Conjugates (LDCs)?
- What are Lipids?
- What are Monodispersed and Polydispersed PEGs?
- What are PEG Lipids?
- What are Phospholipids?
- What are Sterols? - Definition, Structure, Function, Examples and Uses
- What is Biotinylation and Biotinylated PEG?
- What is Click Chemistry?
- What is Hydrogel?
- What is Methoxy Polyethylene Glycol (mPEG)?
- What is Nanogels and Its Applications?
- What is the Formulation of Lipid Nanoparticles (LNPs)?
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