Thiol-PEG8-propionic acid
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| Category | Small-molecule Heterobifunctional PEG |
| Catalog NO. | BPG-2202 |
| Product Name | Thiol-PEG8-propionic acid |
| CAS | 866889-02-3 |
| Molecular Formula | C₁₉H₃₈O₁₀S |
| Molecular Weight | 458.56 |
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| Description | Thiol-PEG8-acid is a polyethylene glycol (PEG)-based PROTAC linker. Thiol-PEG8-acid can be used in the synthesis of a series of PROTACs. |
| Synonyms | HS-PEG8-CH2CH2COOH; 1-mercapto-3,6,9,12,15,18,21,24-Octaoxaheptacosan-27-oic acid |
| IUPAC Name | 3-[2-[2-[2-[2-[2-[2-[2-(2-sulfanylethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid |
| Canonical SMILES | C(COCCOCCOCCOCCOCCOCCOCCOCCS)C(=O)O |
| InChI | InChI=1S/C19H38O10S/c20-19(21)1-2-22-3-4-23-5-6-24-7-8-25-9-10-26-11-12-27-13-14-28-15-16-29-17-18-30/h30H,1-18H2,(H,20,21) |
| InChIKey | SKYJRDAORYSCAL-UHFFFAOYSA-N |
| Boiling Point | 559.7±50.0 °C at 760 mmHg |
| Purity | >95% |
| Density | 1.1±0.1 g/cm3 |
| Appearance | Colorless Liquid |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
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Resources
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Technical Information
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- How to Perform Polyethylene Glycol (PEG) Modification?
- Hydrophobic Interaction Chromatography (HIC) Technique
- Introduction of Polyethylene Glycol (PEG)
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Industry News
- Applications of PEG-DSPE: Drug Carriers and Drug Delivery
- Applications of Polyethylene Glycol (PEG) as Medical Devices
- Classification of Lipid-Based Vaccine Adjuvants
- FDA approved PEGylated Products
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- Hyaluronic Acid & PEGylated Hyaluronic Acid
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- Lipid Formulations: Key Absorption-Enhancing Technologies in New Drug Development
- Lipid-Drug Conjugates (LDCs) for Nanoparticle Drug Delivery
- Liposome in Drug Delivery
- Overview of Liposome Preparation Process
- PEG in Pharmaceutical Preparations (I): Solvents, Lubricants, Adhesives and More
- PEG in Pharmaceutical Preparations (II): Stabilizers, Plasticizers and Modification Materials
- PEG Linkers in Antibody Drug Conjugates and PROTACs
- PEG-DSPE Block Copolymers and Their Derivatives
- PEGylated RGD Peptides: A Promising Tool for Targeted Drug Delivery
- Polyethylene Glycol (PEG) Modified Targeting Nanomaterials
- Preparation Method of PEG Hydrogel
- The PROTAC Technology in Drug Development
- What are Biotinylation and Biotinylated PEG?
- What are Lipid Excipients and Their Applications?
- What are Lipid Nanoparticles and Their Applications?
- What are Lipid-Drug Conjugates (LDCs)?
- What are Lipids?
- What are Monodispersed and Polydispersed PEGs?
- What are PEG Lipids?
- What are Phospholipids?
- What is Click Chemistry?
- What is Hydrogel?
- What is Methoxy Polyethylene Glycol (mPEG)?
- What is Nanogels and Its Applications?
- What is the Formulation of Lipid Nanoparticles (LNPs)?
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