Thiol-PEG5-amine
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| Category | Small-molecule Heterobifunctional PEG |
| Catalog NO. | BPG-1914 |
| Product Name | Thiol-PEG5-amine |
| CAS | 1347750-20-2 |
| Molecular Formula | C₁₂H₂₇NO₅S |
| Molecular Weight | 297.41 |
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| Description | HS-PEG5-CH2CH2NH2 is a polyethylene glycol (PEG)-based PROTAC linker. HS-PEG5-CH2CH2NH2 can be used in the synthesis of a series of PROTACs. |
| Synonyms | Thiol-PEG5-amine |
| IUPAC Name | 2-[2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethanethiol |
| Canonical SMILES | C(COCCOCCOCCOCCOCCS)N |
| InChI | InChI=1S/C12H27NO5S/c13-1-2-14-3-4-15-5-6-16-7-8-17-9-10-18-11-12-19/h19H,1-13H2 |
| InChIKey | CLMWLYNJZRFYHK-UHFFFAOYSA-N |
| Purity | >95% |
| Appearance | Colorless Liquid |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
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Technical Information
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Industry News
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- PEG in Pharmaceutical Preparations (I): Solvents, Lubricants, Adhesives and More
- PEG in Pharmaceutical Preparations (II): Stabilizers, Plasticizers and Modification Materials
- PEG Linkers in Antibody Drug Conjugates and PROTACs
- PEG-DSPE Block Copolymers and Their Derivatives
- PEGylated Drugs: Definition, Structure, Classification and Benefits
- PEGylated RGD Peptides: A Promising Tool for Targeted Drug Delivery
- Pharmacokinetics and Bioanalysis of PEGylated Drugs
- Polyethylene Glycol (PEG) Modified Targeting Nanomaterials
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- The PROTAC Technology in Drug Development
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