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Tetraethylene glycol monohexadecyl ether

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Category Small-molecule Heterobifunctional PEG
Catalog NO. BPG-2121
Product Name Tetraethylene glycol monohexadecyl ether
CAS 5274-63-5
Molecular Formula CH3(CH2)15(OCH2CH2)4OH
Molecular Weight 418.65
Tetraethylene glycol monohexadecyl ether
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Product Information

Description Tetraethylene glycol monohexadecyl ether is a polyethylene glycol (PEG)-based PROTAC linker. Tetraethylene glycol monohexadecyl ether can be used in the synthesis of a series of PROTACs.
Synonyms HEXADECYL TETRAETHYLENE GLYCOL ETHER; HEXADECYLTETRAGLYCOL; C16E4; TETRAETHYLENE GLYCOL MONOHEXADECYL ETHER; polyoxyethylene 4 cetyl ether; CETETH-4; C16E4, Hexadecyl tetraethylene glycol ether, Hexadecyltetraglycol
IUPAC Name 2-[2-[2-(2-hexadecoxyethoxy)ethoxy]ethoxy]ethanol
Canonical SMILES CCCCCCCCCCCCCCCCOCCOCCOCCOCCO
InChI InChI=1S/C24H50O5/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-17-26-19-21-28-23-24-29-22-20-27-18-16-25/h25H,2-24H2,1H3
InChIKey CACXEVGZNASLOU-UHFFFAOYSA-N
Boiling Point 501.5±35.0 °C at 760 mmHg
Purity >95%
Density 0.9±0.1 g/cm3
Appearance colorless solid
Storage Please store the product under the recommended conditions in the Certificate of Analysis.

Tetraethylene glycol monohexadecyl ether, a surfactant with diverse industrial and scientific uses, finds applications in various domains. Here are four key applications highlighted with elevated perplexity and burstiness:

Emulsification: Widely embraced as an emulsifying agent, tetraethylene glycol monohexadecyl ether plays a pivotal role in formulating cosmetics, pharmaceuticals, and food products. Its function lies in stabilizing blends of oil and water, ensuring a harmonious and consistent texture. This attribute leads to heightened product quality and efficacy, culminating in enhanced consumer experience and satisfaction.

Drug Delivery Systems: Within the realm of pharmaceutical investigation, tetraethylene glycol monohexadecyl ether emerges as a central component in crafting drug delivery systems, especially liposomes and micelles. It facilitates the encapsulation and controlled release of therapeutic compounds, thereby bolstering drug stability and bioavailability. This advancement holds the promise of refining the efficacy and safety profiles of a diverse array of medications, ushering in a new era of pharmaceutical innovation.

Analytical Chemistry: Stepping into the domain of analytical chemistry, tetraethylene glycol monohexadecyl ether assumes a key role in sample preparation and chromatographic methodologies aimed at the extraction and separation of analytes. Its surface-active characteristics prove instrumental in augmenting the solubility and separation of compounds within intricate mixtures, fostering a landscape of heightened precision and efficiency in analytical outcomes.

Nanotechnology: Pioneering advancements in the field of nanotechnology, tetraethylene glycol monohexadecyl ether emerges as a crucial agent in the synthesis and stabilization of nanoparticles. Its function as a surfactant extends to overseeing the size and distribution of nanoparticles across various media, underpinning the journey towards developing nanomaterials endowed with tailored properties. These developments hold transformative potential across a spectrum of industries, including medicine and electronics, driving the forefront of innovation and technological progress.

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