TCL053
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| Category | D-Lin-DMA & Analogs |
| Catalog NO. | BPG-3667 |
| Product Name | TCL053 |
| CAS | 2361162-70-9 |
| Molecular Formula | C53H95NO8 |
| Molecular Weight | 874.4 |
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| Description | TCL053 is an ionizable amino lipid that is comprised of three 14-carbon fatty acid tails with single alkene groups in each tail. TCL053 has been used in the generation of lipid nanoparticles (LNPs) and has a pKa value of 6.8. This product is provided as a solution in ethanol. |
| Synonyms | TCL053; 2361162-70-9; (9Z,9'Z)-2-(((4-(Dimethylamino)butanoyl)oxy)methyl)-2-(((Z)-tetradec-9-enoyloxy)methyl)propane-1,3-diyl bis(tetradec-9-enoate); SCHEMBL22580685; EX-A7330; BP-29592; MS-31622; HY-147332 |
| IUPAC Name | [2-[4-(dimethylamino)butanoyloxymethyl]-3-[(Z)-tetradec-9-enoyl]oxy-2-[[(Z)-tetradec-9-enoyl]oxymethyl]propyl] (Z)-tetradec-9-enoate |
| Canonical SMILES | CCCCC=CCCCCCCCC(=O)OCC(COC(=O)CCCCCCCC=CCCCC)(COC(=O)CCCCCCCC=CCCCC)COC(=O)CCCN(C)C |
| InChI | InChI=1S/C53H95NO8/c1-6-9-12-15-18-21-24-27-30-33-36-40-49(55)59-45-53(48-62-52(58)43-39-44-54(4)5,46-60-50(56)41-37-34-31-28-25-22-19-16-13-10-7-2)47-61-51(57)42-38-35-32-29-26-23-20-17-14-11-8-3/h15-20H,6-14,21-48H2,1-5H3/b18-15-,19-16-,20-17- |
| InChIKey | MJPUTLHISFHJJZ-QMJZYSMNSA-N |
| Storage | -20°C |
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Industry News
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- PEG in Pharmaceutical Preparations (I): Solvents, Lubricants, Adhesives and More
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- PEG Linkers in Antibody Drug Conjugates and PROTACs
- PEG-DSPE Block Copolymers and Their Derivatives
- PEGylated RGD Peptides: A Promising Tool for Targeted Drug Delivery
- Polyethylene Glycol (PEG) Modified Targeting Nanomaterials
- Preparation Method of PEG Hydrogel
- The PROTAC Technology in Drug Development
- What are Biotinylation and Biotinylated PEG?
- What are Lipid Excipients and Their Applications?
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- What are Lipid-Drug Conjugates (LDCs)?
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- What is Methoxy Polyethylene Glycol (mPEG)?
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