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Tbdms-PEG10-alcohol

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Category Tbdms-PEGn-alcohol
Catalog NO. BPG-3478
Product Name Tbdms-PEG10-alcohol
CAS 1613506-67-4
Molecular Formula C26H56O11Si
Molecular Weight 572.81
Tbdms-PEG10-alcohol
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Product Information

Description Tbdms-PEG10-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It contains a TBDMS alcohol protecting group and a terminal hydroxyl group. TBDMS can be removed in the presence of acetyl chloride. The hydroxyl group can be derived into other compounds by other reactions. The hydrophilic PEG linker can increase the solubility of compounds in aqueous media.
Synonyms TBDMS-PEG11; TBDMS-PEG10-OH; 2,2,3,3-tetramethyl-4,7,10,13,16,19,22,25,28,31-decaoxa-3-silatritriacontan-33-ol
IUPAC Name 2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[tert-butyl(dimethyl)silyl]oxyethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol
Canonical SMILES C[Si](OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO)(C(C)(C)C)C
InChI InChI=1S/C26H56O11Si/c1-26(2,3)38(4,5)37-25-24-36-23-22-35-21-20-34-19-18-33-17-16-32-15-14-31-13-12-30-11-10-29-9-8-28-7-6-27/h27H,6-25H2,1-5H3
InChIKey GVUHXVYTJPBCQT-UHFFFAOYSA-N
Purity ≥95%
Storage Store at 2-8°C for short term (days to weeks) or -20°C for long term (months to years)

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