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Category NHBoc-PEGn-amine
Catalog NO. BPG-2055
Product Name t-Boc-N-amido-PEG5-amine
CAS 189209-27-6
Molecular Formula C17H36N2O7
Molecular Weight 380.48
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Product Information

Description NH2-PEG5-C2-NH-Boc is a PROTAC linker, which refers to the alkyl/ether composition. NH2-PEG5-C2-NH-Boc can be used in the synthesis of a series of PROTACs. NH2-PEG5-C2-NH-Boc is a PEG derivative containing an amino group and Boc-protected amino group. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The Boc group can be deprotected under mild acidic conditions to form the free amine.
Synonyms NHBoc-PEG5-amine; O-(2-Aminoethyl)-O'-[2-(Boc-amino)ethyl]tetraethylene Glycol; 19-Amino-5,8,11,14,17-pentaoxa-2-azanonadecanoic Acid 1,1-Dimethylethyl Ester; Boc-NH-PEG5-CH2CH2NH2; tert-butyl (17-amino-3,6,9,12,15-pentaoxaheptadecyl)carbamate; NH2-PEG5-C2-NH-Boc; Boc-N-amido-PEG5-Amine; N1-Boc-3,6,9,12,15-pentaoxaheptadecane-1,17-diamine; 5,8,11,14,17-Pentaoxa-2-azanonadecanoic acid, 19-amino-, 1,1-dimethylethyl ester; N-(t-butyloxycarbonyl)-3,6,9,12,15-pentaoxaheptadecane-1,17-diamine; Carbamic acid, N-(17-amino-3,6,9,12,15-pentaoxaheptadec-1-yl)-, 1,1-dimethylethyl ester
IUPAC Name tert-butyl N-[2-[2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethyl]carbamate
InChI InChI=1S/C17H36N2O7/c1-17(2,3)26-16(20)19-5-7-22-9-11-24-13-15-25-14-12-23-10-8-21-6-4-18/h4-15,18H2,1-3H3,(H,19,20)
Boiling Point 480.2±45.0 °C at 760 mmHg
Purity ≥95%
Density 1.1±0.1 g/cm3
Solubility Soluble in DCM, DMF, DMSO, Water
Appearance Pale Yellow or Colorless Oily Matter
Storage Store at 2-8°C, protect from light
Exact Mass 380.25225149
LogP 1.45750


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