t-Boc-N-amido-PEG2-amine

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Category	NHBoc-PEGn-amine
Catalog NO.	BPG-1828
Product Name	t-Boc-N-amido-PEG2-amine
CAS	153086-78-3
Molecular Formula	C11H24N2O4
Molecular Weight	248.32

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Description	Boc-NH-PEG2-C2-NH2 is a PROTAC linker, which refers to the alkyl/ether composition. Boc-NH-PEG2-C2-NH2 can be used in the synthesis of a series of PROTACs. Boc-NH-PEG2-C2-NH2 is a PEG derivative containing an amino group and Boc-protected amino group. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. PEG Linkers may be useful in the development of antibody drug conjugates and PROTACs.
Synonyms	NHBoc-PEG2-amine; Boc-NH-PEG2-C2-NH2; BocNH-PEG2-CH2CH2NH2; N-(tert-Butoxycarbonyl)-3,6-dioxa-1,8-octanediaminetert-Butyl (2-(2-(2-aminoethoxy)ethoxy)ethyl)carbamate; Boc-1-amino-3,6-dioxa-8-octanediamine; N-Boc-2-[2-(2-amino-ethoxy)-ethoxy]-ethylamine; N-Boc-2,2'-(ethylenedioxy)diethylamine; N-Boc-3,6-dioxaoctane-1,8-diamine; Boc-N-amido-PEG2-Amine; N-Boc-3,6-dioxa-1,8-octanediamine; 1-(t-Butyloxycarbonyl-amino)-3,6-dioxa-8-octaneamine
IUPAC Name	tert-butyl N-[2-[2-(2-aminoethoxy)ethoxy]ethyl]carbamate
Canonical SMILES	CC(C)(C)OC(=O)NCCOCCOCCN
InChI	InChI=1S/C11H24N2O4/c1-11(2,3)17-10(14)13-5-7-16-9-8-15-6-4-12/h4-9,12H2,1-3H3,(H,13,14)
InChIKey	OCUICOFGFQENAS-UHFFFAOYSA-N
Boiling Point	365.2±27.0°C (Predicted)
Purity	≥95%
Density	1.046 g/mL at 20°C
Solubility	Soluble in DMSO (10 mm)
Appearance	Light Yellow Oily Liquid
Storage	Store at 2-8°C under inert gas (nitrogen or Argon)
Exact Mass	248.17360725

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