Catalog NO.: BPG-1828

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Category NHBoc-PEGn-amine
Product Name t-Boc-N-amido-PEG2-amine
CAS 153086-78-3
Molecular Formula C11H24N2O4
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Product Information

Description Boc-NH-PEG2-C2-NH2 is a PROTAC linker, which refers to the alkyl/ether composition. Boc-NH-PEG2-C2-NH2 can be used in the synthesis of a series of PROTACs. Boc-NH-PEG2-C2-NH2 is a PEG derivative containing an amino group and Boc-protected amino group. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. PEG Linkers may be useful in the development of antibody drug conjugates and PROTACs.
Synonyms NHBoc-PEG2-amine; Boc-NH-PEG2-C2-NH2; BocNH-PEG2-CH2CH2NH2; N-(tert-Butoxycarbonyl)-3,6-dioxa-1,8-octanediaminetert-Butyl (2-(2-(2-aminoethoxy)ethoxy)ethyl)carbamate; Boc-1-amino-3,6-dioxa-8-octanediamine; N-Boc-2-[2-(2-amino-ethoxy)-ethoxy]-ethylamine; N-Boc-2,2'-(ethylenedioxy)diethylamine; N-Boc-3,6-dioxaoctane-1,8-diamine; Boc-N-amido-PEG2-Amine; N-Boc-3,6-dioxa-1,8-octanediamine; 1-(t-Butyloxycarbonyl-amino)-3,6-dioxa-8-octaneamine
IUPAC Name tert-butyl N-[2-[2-(2-aminoethoxy)ethoxy]ethyl]carbamate
Molecular Weight 248.32
Molecular Formula C11H24N2O4
InChI InChI=1S/C11H24N2O4/c1-11(2,3)17-10(14)13-5-7-16-9-8-15-6-4-12/h4-9,12H2,1-3H3,(H,13,14)
Boiling Point 365.2±27.0°C (Predicted)
Purity ≥95%
Density 1.046 g/mL at 20°C
Solubility Soluble in DMSO (10 mm)
Appearance Light Yellow Oily Liquid
Storage Store at 2-8°C under inert gas (nitrogen or Argon)
Exact Mass 248.17360725


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