SPDP-Val-Cit-PAB-PNP

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Category	SPDP Peptide
Catalog NO.	BPG-4435
Product Name	SPDP-Val-Cit-PAB-PNP
Molecular Formula	C33H39N7O9S2
Molecular Weight	741.8

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Custom Synthesis
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Product Information

Description	SPDP-Val-Cit-PAB-PNP is a cleavable ADC linker featuring an SPDP group, a Val-Cit dipeptide, a para-aminobenzyl (PAB) spacer and a para-nitrophenyl (PNP) carbonate group. SPDP is a thiol-specific covalent linker which forms disulfide bonds with cysteine residues of proteins. Val-Cit-PAB is a protease-cleavable linker which is designed for efficient payload release upon proteolysis. Finally, PNP is a good leaving group which is activated towards nucleophilic attack such as from amines.
Purity	0.98
Storage	-20°C

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