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Propargyl-PEG7-t-butyl ester
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| Category | Propargyl-PEGn-COOtBu |
| Catalog NO. | BPG-2181 |
| Product Name | Propargyl-PEG7-t-butyl ester |
| CAS | 1818294-29-9 |
| Molecular Formula | C22H40O9 |
| Molecular Weight | 448.55 |
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| Description | Propargyl-PEG7-Boc is a polyethylene glycol (PEG)-based PROTAC linker. Propargyl-PEG7-Boc can be used in the synthesis of a series of PROTACs. |
| Synonyms | Propargyl-PEG7-Boc; Propargyl-PEG7-COOtBu; Propargyl-PEG6-CH2COOtBu; Propargyl-PEG6-CH2CH2COOtBu; 4,7,10,13,16,19,22-Heptaoxapentacos-24-ynoic acid, 1,1-dimethylethyl ester; Propargyl-PEG7-tBu ester; 2-Methyl-2-propanyl 4,7,10,13,16,19,22-heptaoxapentacos-24-yn-1-oate |
| IUPAC Name | tert-butyl 3-[2-[2-[2-[2-[2-(2-prop-2-ynoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoate |
| Canonical SMILES | CC(C)(C)OC(=O)CCOCCOCCOCCOCCOCCOCCOCC#C |
| InChI | InChI=1S/C22H40O9/c1-5-7-24-9-11-26-13-15-28-17-19-30-20-18-29-16-14-27-12-10-25-8-6-21(23)31-22(2,3)4/h1H,6-20H2,2-4H3 |
| InChIKey | ZYHHJKFUMHBJSI-UHFFFAOYSA-N |
| Boiling Point | 494.3±40.0°C (Predicted) |
| Purity | >95% |
| Density | 1.059±0.06 g/cm3 (Predicted) |
| Solubility | Soluble in DCM, DMF, DMSO |
| Appearance | Pale Yellow or Colorless Oily Liquid |
| Storage | Store at 2-8°C |
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Industry News
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- PEG in Pharmaceutical Preparations (I): Solvents, Lubricants, Adhesives and More
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- PEG Linkers in Antibody Drug Conjugates and PROTACs
- PEG-DSPE Block Copolymers and Their Derivatives
- PEGylated Drugs: Definition, Structure, Classification and Benefits
- PEGylated RGD Peptides: A Promising Tool for Targeted Drug Delivery
- Pharmacokinetics and Bioanalysis of PEGylated Drugs
- Polyethylene Glycol (PEG) Modified Targeting Nanomaterials
- Preparation Method of PEG Hydrogel
- The PROTAC Technology in Drug Development
- Vaccines: Definition, History, Ingredients, Types and Mechanism of Action
- What are Lipid Excipients and Their Applications?
- What are Lipid Nanoparticles and Their Applications?
- What are Lipid-Drug Conjugates (LDCs)?
- What are Lipids?
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