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Propargyl-PEG4-acid
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| Category | Propargyl-PEGn-acid |
| Catalog NO. | BPG-1846 |
| Product Name | Propargyl-PEG4-acid |
| CAS | 1415800-32-6 |
| Molecular Formula | C12H20O6 |
| Molecular Weight | 260.28 |
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| Description | Propargyl-PEG4-acid is a polyethylene glycol (PEG)-based PROTAC linker. Propargyl-PEG4-acid can be used in the synthesis of a series of PROTACs. |
| Synonyms | 4,7,10,13-Tetraoxahexadec-15-yn-1-oic acid; Propyne-PEG3-CH2CH2COOH; Alkyne-PEG4-COOH; Propargyl-PEG4-COOH; Alkyne-PEG4-acid; Propargyl-PEG3-CH2CH2COOH; 4,7,10,13-tetraoxahexadec-15-ynoic acid; Tetraoxahexadec-15-yn-1-oic acid |
| IUPAC Name | 3-[2-[2-(2-prop-2-ynoxyethoxy)ethoxy]ethoxy]propanoic acid |
| Canonical SMILES | C#CCOCCOCCOCCOCCC(=O)O |
| InChI | InChI=1S/C12H20O6/c1-2-4-15-6-8-17-10-11-18-9-7-16-5-3-12(13)14/h1H,3-11H2,(H,13,14) |
| InChIKey | WMBXAUWIPBFEOK-UHFFFAOYSA-N |
| Boiling Point | 388.0±37.0 °C at 760 mmHg |
| Purity | >97% |
| Density | 1.129±0.06 g/cm3 (Predicted) |
| Solubility | Soluble in DCM, DMF, DMSO, Water |
| Appearance | Pale Yellow or Colorless Oily Matter |
| Storage | Store at 2-8°C |
| Pictogram(s) | Irritant |
| Signal | Warning |
| Precautionary Statement Codes | P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 |
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PEG Derivatives by Functional Group
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Resources
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Technical Information
- Aqueous Two-Phase System (ATPS) Technique
- Capillary Electrophoresis (CE) Technique
- Enzyme-linked immunosorbent assay (ELISA) Technique
- High performance liquid chromatography (HPLC) Technique
- How to Perform Polyethylene Glycol (PEG) Modification?
- Hydrophobic Interaction Chromatography (HIC) Technique
- Introduction of Polyethylene Glycol (PEG)
- Ion Exchange Chromatography (IEX) Technique
- PEG for Chemical Synthesis
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- Polyethylene Glycol (PEG) Modifier Selection Guide
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Industry News
- Applications of PEG-DSPE: Drug Carriers and Drug Delivery
- Applications of Polyethylene Glycol (PEG) as Medical Devices
- Cholesterol: Definition, Structure, Synthesis, Types and Functions
- Classification of Lipid-Based Vaccine Adjuvants
- FDA approved PEGylated Products
- FDA-Approved Antibody-Drug Conjugates up to 2024
- How are Liposomes Different from Micelles?
- How Lipid Nanoparticles (LNPs) Deliver RNA Drugs?
- Hyaluronic Acid & PEGylated Hyaluronic Acid
- Ionizable Lipids for RNA Delivery
- Lipid Classification and Drug Delivery Systems
- Lipid Formulations: Key Absorption-Enhancing Technologies in New Drug Development
- Lipid-Drug Conjugates (LDCs) for Nanoparticle Drug Delivery
- Liposome in Drug Delivery
- Overview of Liposome Preparation Process
- PEG in Pharmaceutical Preparations (I): Solvents, Lubricants, Adhesives and More
- PEG in Pharmaceutical Preparations (II): Stabilizers, Plasticizers and Modification Materials
- PEG Linkers in Antibody Drug Conjugates and PROTACs
- PEG-DSPE Block Copolymers and Their Derivatives
- PEGylated Drugs: Definition, Structure, Classification and Benefits
- PEGylated RGD Peptides: A Promising Tool for Targeted Drug Delivery
- Pharmacokinetics and Bioanalysis of PEGylated Drugs
- Polyethylene Glycol (PEG) Modified Targeting Nanomaterials
- Preparation Method of PEG Hydrogel
- The PROTAC Technology in Drug Development
- Vaccines: Definition, History, Ingredients, Types and Mechanism of Action
- What are Lipid Excipients and Their Applications?
- What are Lipid Nanoparticles and Their Applications?
- What are Lipid-Drug Conjugates (LDCs)?
- What are Lipids?
- What are Monodispersed and Polydispersed PEGs?
- What are PEG Lipids?
- What are Phospholipids?
- What are Sterols? - Definition, Structure, Function, Examples and Uses
- What is Biotinylation and Biotinylated PEG?
- What is Click Chemistry?
- What is Hydrogel?
- What is Methoxy Polyethylene Glycol (mPEG)?
- What is Nanogels and Its Applications?
- What is the Formulation of Lipid Nanoparticles (LNPs)?
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