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Propargyl-PEG1-O-C1-NHS ester

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Category	Propargyl-PEGn-CH2COO-NHS ester
Catalog NO.	BPG-3412
Product Name	Propargyl-PEG1-O-C1-NHS ester
CAS	2244145-13-7
Molecular Formula	C11H13NO6
Molecular Weight	255.22

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Description	Propargyl-PEG1-O-C1-NHS ester is a PEG linker containing a propargyl group and an NHS group. It is amine-reactive, thus, useful for derivatizing biomolecules with an amine group. The propargyl group reacts with azides via copper-catalyzed azide-alkyne Click Chemistry to form a stable triazole bond. The hydrophilic PEG spacer increases solubility in aqueous media.
Synonyms	Propargyl-PEG2-CH2COO-NHS ester; 2,5-Dioxopyrrolidin-1-yl 2-(2-(prop-2-yn-1-yloxy)ethoxy)acetate; 1-{2-[2-(2-Propyn-1-yloxy)ethoxy]acetoxy}-2,5-pyrrolidinedione; 2,5-Pyrrolidinedione, 1-[[2-[2-(2-propyn-1-yloxy)ethoxy]acetyl]oxy]-; propargyl-PEG2-NHS-acetate
IUPAC Name	(2,5-dioxopyrrolidin-1-yl) 2-(2-prop-2-ynoxyethoxy)acetate
Canonical SMILES	C#CCOCCOCC(=O)ON1C(=O)CCC1=O
InChI	InChI=1S/C11H13NO6/c1-2-5-16-6-7-17-8-11(15)18-12-9(13)3-4-10(12)14/h1H,3-8H2
InChIKey	MWWQABAVPFCWSA-UHFFFAOYSA-N
Boiling Point	377.5±50.0°C at 760 mmHg
Purity	≥95%
Density	1.3±0.1 g/cm3
Storage	Store at 2-8°C

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