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NH2-PEG7-COOMe

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Category Amino-PEGn-COOMe
Catalog NO. BPG-0713
Product Name NH2-PEG7-COOMe
Molecular Formula C18H37NO9
Molecular Weight 411.49
NH2-PEG7-COOMe
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Product Information

Synonyms methyl 1-amino-3,6,9,12,15,18,21-heptaoxatetracosan-24-oate
IUPAC Name methyl 3-[2-[2-[2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoate
Canonical SMILES O=C(OC)CCOCCOCCOCCOCCOCCOCCOCCN
InChI InChI=1S/C18H37NO9/c1-21-18(20)2-4-22-6-8-24-10-12-26-14-16-28-17-15-27-13-11-25-9-7-23-5-3-19/h2-17,19H2,1H3
InChIKey DETGQHFSSFIBJK-UHFFFAOYSA-N
Purity ≥95%
Appearance Pale Yellow or Colorless Oily Matter
Storage Store at 2-8°C

NH2-PEG7-COOMe, also recognized as amino-PEG7-methyl ester, stands as a derivative of polyethylene glycol, serving diverse realms within biochemical and biotechnological domains. Here, explore its manifold applications, presented with a high degree of perplexity and burstiness:

Drug Delivery Systems: Embracing NH2-PEG7-COOMe enriches the solubility and bioavailability of therapeutic compounds. By tethering drugs to this PEG derivative, researchers augment drug stability and extend their lifespan within the body. This innovation is pivotal in crafting efficient delivery systems for chemotherapeutic regimens and various pharmaceuticals.

Bioconjugation: The functional units within NH2-PEG7-COOMe empower its engagement in bioconjugation methodologies. It acts as a bridge connecting proteins, peptides, or other biomolecules to diverse surfaces or carriers. This avenue paves the path for constructing biocompatible materials, serving diagnostic assays, biosensors, and therapeutic ventures magnificently.

Surface Modification: NH2-PEG7-COOMe finds its niche in refining nanoparticles and other materials through surface modifications, elevating their biocompatibility and curbing non-specific binding. By affixing PEG chains to surfaces, researchers fashion sterically stabilized particles that resist aggregation, especially beneficial in precision applications like targeted drug payloads and imaging realms.

Protein Purification: Harnessing the PEGylation traits of NH2-PEG7-COOMe is instrumental in protein purification protocols. PEGylated proteins commonly showcase heightened solubility and diminished immunogenicity, simplifying their separation and characterization. This practice, paramount in research and industrial milieus, facilitates the production of premium-grade proteins, catering to diverse applications.

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PEGylation of Peptides and Proteins

PEGylation of Peptides
and Proteins

Reduce the Immunogenicity of Peptide/Protein Drugs

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APPLICATIONS

APPLICATIONS

PEG linkers For Drug

Improved Circulation Half-Life

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