NH2-PEG4-CH2COOtBu
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| Category | Amino-PEGn-CH2COOtBu |
| Catalog NO. | BPG-0720 |
| Product Name | NH2-PEG4-CH2COOtBu |
| CAS | 864680-64-8 |
| Molecular Formula | C14H29NO6 |
| Molecular Weight | 307.39 |
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| Description | H2N-PEG4-CH2COOtBu is a polyethylene glycol (PEG)-based PROTAC linker. H2N-PEG4-CH2COOtBu can be used in the synthesis of a series of PROTACs. |
| Synonyms | Amino-PEG4-t-butyl acetate; Amino-PEG4-CH2CO2tBu; Amino-PEG4-C1-Boc; Amine-PEG4-CH2COOtBu; Amino-PEG4-CH2CO2-t-butyl ester; 3,6,9,12-Tetraoxatetradecanoic acid, 14-amino-, 1,1-dimethylethyl ester; tert-Butyl 14-Amino-3,6,9,12-tetraoxa-1-tetradecanoate; 2-{2-[2-(2-aminoethoxy)-ethoxy]ethoxy}ethoxy)acetic acid tert-butyl ester |
| IUPAC Name | tert-butyl 2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]acetate |
| Canonical SMILES | CC(C)(C)OC(=O)COCCOCCOCCOCCN |
| InChI | InChI=1S/C14H29NO6/c1-14(2,3)21-13(16)12-20-11-10-19-9-8-18-7-6-17-5-4-15/h4-12,15H2,1-3H3 |
| InChIKey | WPWIGTOQNITKON-UHFFFAOYSA-N |
| Boiling Point | 386.1±32.0°C (Predicted) |
| Purity | ≥95% |
| Density | 1.051±0.06 g/cm3 (Predicted) |
| Solubility | In H2O: 50 mg/mL (162.67 mM; Need ultrasonic) In DMSO: 20 mg/mL (65.07 mM; Need ultrasonic) |
| Storage | Store at 2-8°C |
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Industry News
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- PEG Linkers in Antibody Drug Conjugates and PROTACs
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- PEGylated RGD Peptides: A Promising Tool for Targeted Drug Delivery
- Polyethylene Glycol (PEG) Modified Targeting Nanomaterials
- Preparation Method of PEG Hydrogel
- The PROTAC Technology in Drug Development
- What are Biotinylation and Biotinylated PEG?
- What are Lipid Excipients and Their Applications?
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