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m-PEG12-amine

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Category m-PEGn-amine
Catalog NO. BPG-2345
Product Name m-PEG12-amine
CAS 1977493-48-3
Molecular Formula C25H53NO12
Molecular Weight 559.69
m-PEG12-amine
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Product Information

Description m-PEG12-amine is a non-cleavable 12 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). It is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
Synonyms mPEG12-NH2; Methyl-PEG12-amine
IUPAC Name 2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanamine
Canonical SMILES COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN
InChI InChI=1S/C25H53NO12/c1-27-4-5-29-8-9-31-12-13-33-16-17-35-20-21-37-24-25-38-23-22-36-19-18-34-15-14-32-11-10-30-7-6-28-3-2-26/h2-26H2,1H3
InChIKey MSKSQCLPULZWNO-UHFFFAOYSA-N
Boiling Point 583.6±45.0°C at 760 mmHg
Flash Point 291.3±22.4 °C
Purity >95%
Density 1.073±0.06 g/cm3
Solubility Soluble in Water, DMSO, DCM, DMF
Appearance Colorless to light yellow
Shelf Life 0-4℃ for short term (days to weeks), or -20℃ for long term (months).
Storage Store at 2-8°C

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PEGylation of Peptides and Proteins

PEGylation of Peptides
and Proteins

Reduce the Immunogenicity of Peptide/Protein Drugs

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