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MeNH-PEG1-NHMe

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Category MeNH-PEGn-NHMe
Catalog NO. BPG-3594
Product Name MeNH-PEG1-NHMe
CAS 2620-27-1
Molecular Formula C6H16N2O
Molecular Weight 132.21
MeNH-PEG1-NHMe
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Product Information

Description MeNH-PEG1-NHMe, a PEGylated entity employed in pharmaceutical drug delivery mechanisms for the augmentation of solubility and stability. It is frequently utilized within the pharmaceutical domain to combat a range of illnesses through the enhancement of drug pharmacokinetics.
Synonyms 2,2'-oxybis(N-methylethan-1-amine); 1,5-Bis(methylamino)-3-oxapentane; 2,2'-oxybis(N-methylethanamine); N-methyl-2-(methylaminoethyloxy)ethylamine; N-methyl-N-{2-[2-(methylamino)ethoxy]ethyl}amine; methyl ({2-[2-(methylamino)ethoxy]ethyl})amine
IUPAC Name N-methyl-2-[2-(methylamino)ethoxy]ethanamine
Canonical SMILES CNCCOCCNC
InChI InChI=1S/C6H16N2O/c1-7-3-5-9-6-4-8-2/h7-8H,3-6H2,1-2H3
InChIKey VXPJBVRYAHYMNY-UHFFFAOYSA-N
Boiling Point 165.8±15.0°C at 760 mmHg
Purity ≥95%
Density 0.872±0.06 g/cm3 (Predicted)
Related CAS 55952-31-3 (polymer)
Appearance Clear Slightly Yellow Liquid
Storage Store at 2-8°C

MeNH-PEG1-NHMe, also recognized as N-Methylated Polyethylene Glycol, stands as a versatile chemical compound with multifaceted applications across diverse scientific domains. Here we present four key applications of MeNH-PEG1-NHMe, with a heightened degree of perplexity and burstiness:

Drug Delivery Systems: Harnessing the potent properties of MeNH-PEG1-NHMe, scientists revolutionize drug solubility and stability. By coupling pharmaceutical drugs with this hydrophilic PEG structure, their persistence in the body is extended, amplifying therapeutic efficacy significantly. This innovative approach not only prolongs drug circulation but also addresses issues of immunogenicity and toxicity associated with drug compounds.

Bioconjugation: Within the intricate realm of bioconjugation, MeNH-PEG1-NHMe emerges as a pivotal agent for linking biomolecules like proteins, antibodies, and nucleic acids. Its molecular architecture enables stable and flexible cross-linking, paving the way for the creation of versatile bioconjugates crucial for applications in diagnostics, therapeutics, and biosensing. This strategic conjugation heralds new horizons in the domain of biomolecular interactions.

Nanoparticle Functionalization: MeNH-PEG1-NHMe assumes a vital role in enhancing nanoparticle surfaces to improve biocompatibility and targeting precision. By encapsulating nanoparticles with a PEG coating, researchers navigate immune system clearance, enabling precise delivery to targeted cells or tissues. This groundbreaking approach enhances the potential of nanoparticles in drug delivery and imaging realms.

Surface Modification of Biomaterials: In the arenas of tissue engineering and regenerative medicine, MeNH-PEG1-NHMe emerges as a transformative element in optimizing biomaterial interactions with biological tissues. PEGylation of biomaterial surfaces effectively thwarts undesirable protein adsorption and cell adhesion, curbing fouling and elevating overall biocompatibility standards.

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PEGylation of Peptides and Proteins

PEGylation of Peptides
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