Mal-Ph-CONH-PEG11-NHS ester
* Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Category | Mal-Ph-CONH-PEGn-NHS ester |
Catalog NO. | BPG-0421 |
Product Name | Mal-Ph-CONH-PEG11-NHS ester |
Molecular Formula | C40H59N3O18 |
Molecular Weight | 869.92 |
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Description | Mal-Ph-CONH-PEG11-NHS ester is a non-cleavable 11-unit PEG ADC linker that is used in the synthesis of antibody-conjugated drugs (ADCs). |
Synonyms | 2,5-dioxopyrrolidin-1-yl 1-(3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)phenyl)-1-oxo-5,8,11,14,17,20,23,26,29,32,35-undecaoxa-2-azaoctatriacontan-38-oate |
IUPAC Name | (2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[[3-(2,5-dioxopyrrol-1-yl)benzoyl]amino]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoate |
Canonical SMILES | O=C(ON1C(CCC1=O)=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(C2=CC=CC(N3C(C=CC3=O)=O)=C2)=O |
InChI | InChI=1S/C40H59N3O18/c44-35-4-5-36(45)42(35)34-3-1-2-33(32-34)40(49)41-9-11-51-13-15-53-17-19-55-21-23-57-25-27-59-29-31-60-30-28-58-26-24-56-22-20-54-18-16-52-14-12-50-10-8-39(48)61-43-37(46)6-7-38(43)47/h1-5,32H,6-31H2,(H,41,49) |
InChIKey | JYNQKVHCQVAXIJ-UHFFFAOYSA-N |
Purity | ≥95% |
Storage | Store at 2-8°C |
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Resources
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Technical Information
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- How to Perform Polyethylene Glycol (PEG) Modification?
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Industry News
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- Liposome in Drug Delivery
- Overview of Liposome Preparation Process
- PEG in Pharmaceutical Preparations (I): Solvents, Lubricants, Adhesives and More
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- PEG Linkers in Antibody Drug Conjugates and PROTACs
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- Polyethylene Glycol (PEG) Modified Targeting Nanomaterials
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- The PROTAC Technology in Drug Development
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PEGylation of Peptides
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