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Mal-PEG9-acid
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| Category | Mal-PEGn-acid |
| Catalog NO. | BPG-0344 |
| Product Name | Mal-PEG9-acid |
| Molecular Formula | C25H43NO13 |
| Molecular Weight | 565.61 |
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| Description | Mal-PEG9-acid is a non-cleavable 9-unit PEG ADC linker that is used in the synthesis of antibody conjugated drugs (ADCs). It is also a PROTAC linker, belonging to the PEG class, which can be used to synthesize PROTAC molecules. |
| Synonyms | Mal-PEG9-CH2CH2COOH; Maleimide-PEG9-CH2CH2COOH; Mal-PEG9-COOH; Mal-PEG9-propionic acid; 1-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3,6,9,12,15,18,21,24,27-nonaoxatriacontan-30-oic acid |
| IUPAC Name | 3-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2,5-dioxopyrrol-1-yl)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid |
| Canonical SMILES | O=C(O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCN1C(C=CC1=O)=O |
| InChI | InChI=1S/C25H43NO13/c27-23-1-2-24(28)26(23)4-6-32-8-10-34-12-14-36-16-18-38-20-22-39-21-19-37-17-15-35-13-11-33-9-7-31-5-3-25(29)30/h1-2H,3-22H2,(H,29,30) |
| InChIKey | YRKWESNSKKDDGX-UHFFFAOYSA-N |
| Purity | ≥95% |
| Related CAS | 357277-61-3 (polymer) 2422928-26-3 (polymer) |
| Appearance | Light Yellow or White Solid |
| Storage | Store at 2-8°C |
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Technical Information
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Industry News
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- Overview of Liposome Preparation Process
- PEG in Pharmaceutical Preparations (I): Solvents, Lubricants, Adhesives and More
- PEG in Pharmaceutical Preparations (II): Stabilizers, Plasticizers and Modification Materials
- PEG Linkers in Antibody Drug Conjugates and PROTACs
- PEG-DSPE Block Copolymers and Their Derivatives
- PEGylated Drugs: Definition, Structure, Classification and Benefits
- PEGylated RGD Peptides: A Promising Tool for Targeted Drug Delivery
- Pharmacokinetics and Bioanalysis of PEGylated Drugs
- Polyethylene Glycol (PEG) Modified Targeting Nanomaterials
- Preparation Method of PEG Hydrogel
- The PROTAC Technology in Drug Development
- Vaccines: Definition, History, Ingredients, Types and Mechanism of Action
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- What are Lipid Nanoparticles and Their Applications?
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PEGylation of Peptides
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Reduce the Immunogenicity of Peptide/Protein Drugs
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PEG linkers For Drug
Improved Circulation Half-Life
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