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Mal-PEG2-acid

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Category	Mal-PEGn-acid
Catalog NO.	BPG-1843
Product Name	Mal-PEG2-acid
CAS	1374666-32-6
Molecular Formula	C11H15NO6
Molecular Weight	257.24

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Description	Mal-PEG2-acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Mal-PEG2-acid can be conjugated to Tubulysin (HY-128914) and its derivative cytotoxic molecule.
Synonyms	Mal-PEG2-CH2CH2COOH; Maleimide-PEG2-CH2CH2COOH; Mal-PEG2-COOH; Mal-PEG2-propionic acid; 3-(2-(2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethoxy)ethoxy)propanoic acid; Propanoic acid, 3-[2-[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethoxy]ethoxy]-
IUPAC Name	3-[2-[2-(2,5-dioxopyrrol-1-yl)ethoxy]ethoxy]propanoic acid
Canonical SMILES	C1=CC(=O)N(C1=O)CCOCCOCCC(=O)O
InChI	InChI=1S/C11H15NO6/c13-9-1-2-10(14)12(9)4-6-18-8-7-17-5-3-11(15)16/h1-2H,3-8H2,(H,15,16)
InChIKey	TXMDOUPVKVGPIS-UHFFFAOYSA-N
Boiling Point	455.7±35.0 °C at 760 mmHg
Flash Point	229.4±25.9 °C
Purity	≥95%
Density	1.329±0.06 g/cm3 (Predicted)
Solubility	Soluble in DMSO (10 mm)
Related CAS	357277-61-3 (polymer) 2422928-26-3 (polymer)
Appearance	White to Light Yellow Powder to Crystal
Shelf Life	0-4°C for short term (days to weeks), or -20°C for long term (months).
Storage	Store at 2-8°C
Vapor Pressure	0.0±2.4 mmHg at 25°C
LogP	-0.73
Pictogram(s)	Irritant
Signal	Warning
Precautionary Statement Codes	P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

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