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Mal-amido-PEG9-DNP

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Category Mal-amido-PEGn-DNP
Catalog NO. BPG-1689
Product Name Mal-amido-PEG9-DNP
Molecular Formula C33H51N5O16
Molecular Weight 773.79
Mal-amido-PEG9-DNP
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Product Information

Synonyms N-(29-((2,4-dinitrophenyl)amino)-3,6,9,12,15,18,21,24,27-nonaoxanonacosyl)-3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanamide
IUPAC Name N-(2-(2-(2-(2-(2-(2-(2-(2-(2-(2-((2,4-dinitrophenyl)amino)ethoxy)ethoxy)ethoxy)ethoxy)ethoxy)ethoxy)ethoxy)ethoxy)ethoxy)ethyl)-3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanamide
Canonical SMILES O=C(NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC1=CC=C([N+]([O-])=O)C=C1[N+]([O-])=O)CCN2C(C=CC2=O)=O
InChI InChI=1S/C33H51N5O16/c39-31(5-8-36-32(40)3-4-33(36)41)35-7-10-47-12-14-49-16-18-51-20-22-53-24-26-54-25-23-52-21-19-50-17-15-48-13-11-46-9-6-34-29-2-1-28(37(42)43)27-30(29)38(44)45/h1-4,27,34H,5-26H2,(H,35,39)
InChIKey ZOZSAZPXPWMRDL-UHFFFAOYSA-N
Purity ≥95%
Appearance Yellow Powder
Storage Store at 2-8°C

Mal-amido-PEG9-DNP, a versatile chemical compound with diverse applications in biochemical and biotechnological fields, is at the forefront of innovation. Here are four key applications of Mal-amido-PEG9-DNP presented with high perplexity and burstiness:

Targeted Drug Delivery: Within the realm of precision medicine, Mal-amido-PEG9-DNP plays a crucial role in developing targeted drug delivery systems. By conjugating this compound with therapeutic agents, scientists enable the precise delivery of drugs to specific cells or tissues, minimizing off-target effects and maximizing treatment efficacy. In cancer therapy, this method holds immense promise as targeted drug delivery enhances the therapeutic index of chemotherapeutic agents, ultimately improving patient outcomes.

Protein Modification: In the pursuit of structural and functional analysis of proteins, researchers frequently turn to Mal-amido-PEG9-DNP for its versatility in protein modification. By attaching this compound to select amino acid residues, scientists can introduce functional groups or labels for subsequent detection and analysis. This modification technique is pivotal in proteomics and biophysical studies, providing valuable insights into protein interactions and dynamics, thereby deepening our understanding of biological processes.

Bioconjugation: Serving as a pivotal linker in bioconjugation processes, Mal-amido-PEG9-DNP facilitates the creation of intricate bioconjugates by bridging biomolecules with synthetic or natural components. This compound's versatility enables the development of multifaceted bioconjugates for various applications such as diagnostics, imaging, and biosensors. The inclusion of a PEG spacer enhances solubility and reduces steric hindrance, streamlining the bioconjugation process and enhancing efficiency in molecular interactions.

Immunohistochemistry: In the realm of immunohistochemistry, Mal-amido-PEG9-DNP emerges as a valuable tool for labeling antibodies or other biomolecules to detect specific antigens in tissue samples. The distinctive DNP moiety serves as a recognizable tag that can be visualized using appropriate detection methods. This technique is indispensable for investigating tissue-specific expression patterns and aiding in the diagnosis of various diseases, thus playing a crucial role in advancing our understanding of pathological processes.

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PEGylation of Peptides and Proteins

PEGylation of Peptides
and Proteins

Reduce the Immunogenicity of Peptide/Protein Drugs

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