Mal-amido-PEG1-TFP ester
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| Category | Mal-amido-PEGn-TFP ester |
| Catalog NO. | BPG-0339 |
| Product Name | Mal-amido-PEG1-TFP ester |
| Molecular Formula | C18H16F4N2O6 |
| Molecular Weight | 432.33 |
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| Description | Mal-amido-PEG1-TFP ester is a PEG linker containing a maleimide and TFP ester end group. The Maleimide group is reactive with thiols between pH 6.5 and 7.5. The TFP ester can react with primary amine groups and is also less susceptible to undergo hydrolysis compared to NHS ester. The hydrophilic PEG chain increases the water solubility of a compound in aqueous media. |
| Synonyms | Mal-NH-PEG1-TFP; MAL-PEG1-TFP ester; MAL-dPEG1-TFP ester; 2,3,5,6-tetrafluorophenyl 3-(2-(3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanamido)ethoxy)propanoate |
| IUPAC Name | (2,3,5,6-tetrafluorophenyl) 3-[2-[3-(2,5-dioxopyrrol-1-yl)propanoylamino]ethoxy]propanoate |
| Canonical SMILES | O=C(OC1=C(F)C(F)=CC(F)=C1F)CCOCCNC(CCN2C(C=CC2=O)=O)=O |
| InChI | InChI=1S/C18H16F4N2O6/c19-10-9-11(20)17(22)18(16(10)21)30-15(28)4-7-29-8-5-23-12(25)3-6-24-13(26)1-2-14(24)27/h1-2,9H,3-8H2,(H,23,25) |
| InChIKey | BXSQNNHCEOFYNK-UHFFFAOYSA-N |
| Purity | ≥95% |
| Storage | Store at 2-8°C |
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