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Lipoamido-PEG4-acid

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Category Lipoamido-PEGn-acid
Catalog NO. BPG-0294
Product Name Lipoamido-PEG4-acid
CAS 1314378-10-3
Molecular Formula C19H35NO7S2
Molecular Weight 453.61
Lipoamido-PEG4-acid
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Description Lipoamido-PEG4-acid is a PEG linker containing a lipoic acid group and a terminal carboxylic acid. Lipoic acid contains two sulfur atoms (at C6 and C8) connected by a disulfide bond and is thus considered to be oxidized although either sulfur atom can exist in higher oxidation states. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The hydrophilic PEG linker increases the water solubility of the compound.
Synonyms Lipoamido-PEG4-CH2CH2COOH; LA-PEG4-COOH; Lipoamido-PEG4-COOH; 3-[2-[2-[2-[2-[5-(dithiolan-3-yl)pentanoylamino]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid; 4,7,10,13-Tetraoxa-16-azaheneicosanoic acid, 21-(1,2-dithiolan-3-yl)-17-oxo-; 21-(1,2-Dithiolan-3-yl)-17-oxo-4,7,10,13-tetraoxa-16-azahenicosan-1-oic acid
IUPAC Name 3-(2-(2-(2-(2-(5-(1,2-dithiolan-3-yl)pentanamido)ethoxy)ethoxy)ethoxy)ethoxy)propanoic acid
Canonical SMILES C1CSSC1CCCCC(=O)NCCOCCOCCOCCOCCC(=O)O
InChI InChI=1S/C19H35NO7S2/c21-18(4-2-1-3-17-6-16-28-29-17)20-7-9-25-11-13-27-15-14-26-12-10-24-8-5-19(22)23/h17H,1-16H2,(H,20,21)(H,22,23)
InChIKey QJFPDZROPSGMGV-UHFFFAOYSA-N
Purity ≥95%
Density 1.2±0.1 g/cm3
Solubility Soluble in DMSO
Appearance Light Yellow or White Solid
Storage Store at 2-8°C for short term (days to weeks) or -20°C for long term (months to years)

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