Lipoamido-PEG10-acid
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| Category | Lipoamido-PEGn-acid |
| Catalog NO. | BPG-0292 |
| Product Name | Lipoamido-PEG10-acid |
| Molecular Formula | C31H59NO13S2 |
| Molecular Weight | 717.93 |
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| Description | Lipoamido-PEG10-acid is a PEG linker containing a lipoic acid group and a terminal carboxylic acid. Lipoic acid contains two sulfur atoms (at C6 and C8) connected by a disulfide bond and is thus considered to be oxidized although either sulfur atom can exist in higher oxidation states. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The hydrophilic PEG linker increases the water solubility of the compound. |
| Synonyms | Lipoamido-PEG10-CH2CH2COOH; 39-(1,2-dithiolan-3-yl)-35-oxo-4,7,10,13,16,19,22,25,28,31-decaoxa-34-azanonatriacontanoic acid |
| IUPAC Name | 3-(2-(2-(2-(2-(2-(2-(2-(2-(2-(2-(5-(1,2-dithiolan-3-yl)pentanamido)ethoxy)ethoxy)ethoxy)ethoxy)ethoxy)ethoxy)ethoxy)ethoxy)ethoxy)ethoxy)propanoic acid |
| Canonical SMILES | O=C(O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCCCC1SSCC1)=O |
| InChI | InChI=1S/C31H59NO13S2/c33-30(4-2-1-3-29-6-28-46-47-29)32-7-9-37-11-13-39-15-17-41-19-21-43-23-25-45-27-26-44-24-22-42-20-18-40-16-14-38-12-10-36-8-5-31(34)35/h29H,1-28H2,(H,32,33)(H,34,35) |
| InChIKey | QKUVVERYJIXKIX-UHFFFAOYSA-N |
| Purity | ≥95% |
| Storage | Store at 2-8°C |
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Resources
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Technical Information
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Industry News
- Applications of PEG-DSPE: Drug Carriers and Drug Delivery
- Applications of Polyethylene Glycol (PEG) as Medical Devices
- Classification of Lipid-Based Vaccine Adjuvants
- FDA approved PEGylated Products
- How are Liposomes Different from Micelles?
- How Lipid Nanoparticles (LNPs) Deliver RNA Drugs?
- Hyaluronic Acid & PEGylated Hyaluronic Acid
- Ionizable Lipids for RNA Delivery
- Lipid Classification and Drug Delivery Systems
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- Liposome in Drug Delivery
- Overview of Liposome Preparation Process
- PEG in Pharmaceutical Preparations (I): Solvents, Lubricants, Adhesives and More
- PEG in Pharmaceutical Preparations (II): Stabilizers, Plasticizers and Modification Materials
- PEG Linkers in Antibody Drug Conjugates and PROTACs
- PEG-DSPE Block Copolymers and Their Derivatives
- PEGylated RGD Peptides: A Promising Tool for Targeted Drug Delivery
- Polyethylene Glycol (PEG) Modified Targeting Nanomaterials
- Preparation Method of PEG Hydrogel
- The PROTAC Technology in Drug Development
- What are Biotinylation and Biotinylated PEG?
- What are Lipid Excipients and Their Applications?
- What are Lipid Nanoparticles and Their Applications?
- What are Lipid-Drug Conjugates (LDCs)?
- What are Lipids?
- What are Monodispersed and Polydispersed PEGs?
- What are PEG Lipids?
- What are Phospholipids?
- What is Click Chemistry?
- What is Hydrogel?
- What is Methoxy Polyethylene Glycol (mPEG)?
- What is Nanogels and Its Applications?
- What is the Formulation of Lipid Nanoparticles (LNPs)?
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