Hydroxy-PEG2-t-butyl ester
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| Category | HO-PEGn-COOtBu |
| Catalog NO. | BPG-1805 |
| Product Name | Hydroxy-PEG2-t-butyl ester |
| CAS | 133803-81-3 |
| Molecular Formula | C11H22O5 |
| Molecular Weight | 234.29 |
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| Description | Hydroxy-PEG2-(CH2)2-Boc is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Hydroxy-PEG2-(CH2)2-Boc is extracted from patent WO2004008101A2 (compound 196). |
| Synonyms | HO-PEG2-CH2CH2COOtBu; Hydroxy-PEG2-(CH2)2-Boc; OH-PEG2-TBA; OH-PEG2-CH2CH2COOtBu; HO-PEG2-t-butyl ester; Propanoic acid, 3-[2-(2-hydroxyethoxy)ethoxy]-, 1,1-dimethylethyl ester; t-Butyl 9-hydroxy-4,7-dioxanonanoate; 3-[2-(2-hydroxyethoxy)ethoxy]propionic acid t-butyl ester; 2-Methyl-2-propanyl 3-[2-(2-hydroxyethoxy)ethoxy]propanoate |
| IUPAC Name | tert-butyl 3-[2-(2-hydroxyethoxy)ethoxy]propanoate |
| Canonical SMILES | CC(C)(C)OC(=O)CCOCCOCCO |
| InChI | InChI=1S/C11H22O5/c1-11(2,3)16-10(13)4-6-14-8-9-15-7-5-12/h12H,4-9H2,1-3H3 |
| InChIKey | OKOWESVURLUVMD-UHFFFAOYSA-N |
| Boiling Point | 321.8±22.0 °C at 760 mmHg |
| Purity | ≥95% |
| Density | 1.046±0.1 g/cm3 |
| Solubility | Soluble in DMSO (10 mm) |
| Appearance | Pale Yellow or Colorless Oily Liquid |
| Storage | Store at 2-8°C |
| Exact Mass | 234.1467238 |
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Industry News
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- Preparation Method of PEG Hydrogel
- The PROTAC Technology in Drug Development
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- What are Lipid Excipients and Their Applications?
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PEGylation of Peptides
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Reduce the Immunogenicity of Peptide/Protein Drugs
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