Hydroxy-PEG1-acid
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| Category | HO-PEGn-COOH |
| Catalog NO. | BPG-0643 |
| Product Name | Hydroxy-PEG1-acid |
| CAS | 89211-34-7 |
| Molecular Formula | C5H10O4 |
| Molecular Weight | 134.13 |
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| Description | Hydroxy-PEG1-acid is a non-cleavable 1-unit PEG linker that can be used to synthesize antibody-conjugated drugs (ADCs). |
| Synonyms | OH-PEG1-COOH; HO-PEG1-Propionic acid; HO-PEG1-CH2CH2COOH; Hydroxy-PEG1-propionic acid; 3-(2-hydroxyethoxy)propionic acid; Propanoic acid, 3-(2-hydroxyethoxy)- |
| IUPAC Name | 3-(2-hydroxyethoxy)propanoic acid |
| Canonical SMILES | C(COCCO)C(=O)O |
| InChI | InChI=1S/C5H10O4/c6-2-4-9-3-1-5(7)8/h6H,1-4H2,(H,7,8) |
| InChIKey | GTIFLSYPOXYYFG-UHFFFAOYSA-N |
| Boiling Point | 127-130°C at 2 Torr |
| Purity | ≥95% |
| Density | 1.224±0.06 g/cm3 (Predicted) |
| Solubility | Soluble in DMSO |
| Appearance | Pale Yellow or Colorless Oily Matter |
| Shelf Life | 0-4℃ for short term (days to weeks), or -20℃ for long term (months). |
| Storage | Store at 2-8°C |
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Resources
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Technical Information
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- Introduction of Polyethylene Glycol (PEG)
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Industry News
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- FDA approved PEGylated Products
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- Lipid Classification and Drug Delivery Systems
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- Overview of Liposome Preparation Process
- PEG in Pharmaceutical Preparations (I): Solvents, Lubricants, Adhesives and More
- PEG in Pharmaceutical Preparations (II): Stabilizers, Plasticizers and Modification Materials
- PEG Linkers in Antibody Drug Conjugates and PROTACs
- PEG-DSPE Block Copolymers and Their Derivatives
- PEGylated RGD Peptides: A Promising Tool for Targeted Drug Delivery
- Polyethylene Glycol (PEG) Modified Targeting Nanomaterials
- Preparation Method of PEG Hydrogel
- The PROTAC Technology in Drug Development
- What are Biotinylation and Biotinylated PEG?
- What are Lipid Excipients and Their Applications?
- What are Lipid Nanoparticles and Their Applications?
- What are Lipid-Drug Conjugates (LDCs)?
- What are Lipids?
- What are Monodispersed and Polydispersed PEGs?
- What are PEG Lipids?
- What are Phospholipids?
- What is Click Chemistry?
- What is Hydrogel?
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- What is the Formulation of Lipid Nanoparticles (LNPs)?
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PEGylation of Peptides
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Reduce the Immunogenicity of Peptide/Protein Drugs
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