Fmoc-NH-PEG12-t-butyl ester
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| Category | Fmoc-NH-PEGn-t-butyl ester |
| Catalog NO. | BPG-0235 |
| Product Name | Fmoc-NH-PEG12-t-butyl ester |
| Molecular Formula | C46H73NO16 |
| Molecular Weight | 896.08 |
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| Description | Fmoc-NH-PEG12-t-butyl ester is a polyethylene glycol (PEG)-based PROTAC linker that can be used in the synthesis of a series of PROTACs. |
| Synonyms | Fmoc-N-amido-PEG12-t-butyl ester; tert-butyl 1-(9H-fluoren-9-yl)-3-oxo-2,7,10,13,16,19,22,25,28,31,34,37,40-tridecaoxa-4-azatritetracontan-43-oate |
| IUPAC Name | tert-butyl 3-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(9H-fluoren-9-ylmethoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoate |
| Canonical SMILES | O=C(OC(C)(C)C)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O |
| InChI | InChI=1S/C46H73NO16/c1-46(2,3)63-44(48)12-14-50-16-18-52-20-22-54-24-26-56-28-30-58-32-34-60-36-37-61-35-33-59-31-29-57-27-25-55-23-21-53-19-17-51-15-13-47-45(49)62-38-43-41-10-6-4-8-39(41)40-9-5-7-11-42(40)43/h4-11,43H,12-38H2,1-3H3,(H,47,49) |
| InChIKey | RHPBLBDNHDUGHC-UHFFFAOYSA-N |
| Purity | ≥95% |
| Storage | Store at 2-8°C |
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Technical Information
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Industry News
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- PEG in Pharmaceutical Preparations (I): Solvents, Lubricants, Adhesives and More
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- PEG Linkers in Antibody Drug Conjugates and PROTACs
- PEG-DSPE Block Copolymers and Their Derivatives
- PEGylated RGD Peptides: A Promising Tool for Targeted Drug Delivery
- Polyethylene Glycol (PEG) Modified Targeting Nanomaterials
- Preparation Method of PEG Hydrogel
- The PROTAC Technology in Drug Development
- What are Biotinylation and Biotinylated PEG?
- What are Lipid Excipients and Their Applications?
- What are Lipid Nanoparticles and Their Applications?
- What are Lipid-Drug Conjugates (LDCs)?
- What are Lipids?
- What are Monodispersed and Polydispersed PEGs?
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- What is Click Chemistry?
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