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Fmoc-N-amido-PEG5-propionic acid

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Category	Fmoc-N-amido-PEGn-acid
Catalog NO.	BPG-2306
Product Name	Fmoc-N-amido-PEG5-propionic acid
CAS	882847-32-7
Molecular Formula	C28H37NO9
Molecular Weight	531.59

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Description	Fmoc-N-amido-PEG5-propionic acid is a PEG linker containing a Fmoc-protected amine and a terminal carboxylic acid. The Fmoc group can be deprotected under the basic conditions to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media.
Synonyms	Fmoc-N-amido-PEG5-acid; 1-(9H-Fluoren-9-yl)-3-oxo-2,7,10,13,16,19-hexaoxa-4-azadocosan-22-oic acid; Fmoc-NH-PEG5-CH2CH2COOH; 5,8,11,14,17-Pentaoxa-2-azaeicosanedioic acid, 1-(9H-fluoren-9-ylmethyl) ester; 2,7,10,13,16,19-Hexaoxa-4-azadocosan-22-oic acid, 1-(9H-fluoren-9-yl)-3-oxo-; Fmoc-PEG5-propionic acid
IUPAC Name	3-[2-[2-[2-[2-[2-(9H-fluoren-9-ylmethoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid
Canonical SMILES	C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NCCOCCOCCOCCOCCOCCC(=O)O
InChI	InChI=1S/C28H37NO9/c30-27(31)9-11-33-13-15-35-17-19-37-20-18-36-16-14-34-12-10-29-28(32)38-21-26-24-7-3-1-5-22(24)23-6-2-4-8-25(23)26/h1-8,26H,9-21H2,(H,29,32)(H,30,31)
InChIKey	TWQTXZPTZPOEEB-UHFFFAOYSA-N
Boiling Point	711.4±60.0 °C at 760 mmHg
Purity	≥95%
Density	1.210±0.06 g/cm3 at 20°C, 760 Torr
Related CAS	850312-72-0 (polymer)
Appearance	Colorless to yellow viscous liquid
Storage	Store at 2-8°C
Exact Mass	531.24683176
LogP	3.47370

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